Protein Alignment TkR86C and AstA-R2

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Alignment Length: 388
• Identity: 106/388 - (27%)
• Similarity: 178/388 - (45%)
• Gaps: 58/388 - (14%)

  Fly    28 NTTLLG--SLNRTEVVSLLSSIIDNRDNLESINEAKDFLT--ECLFPSPTRPYELPWEQKTIWAI 88
            |||:|.  |||.|.          |.:|:.|      |.|  |.|..:.|    |||    |...
  Fly     3 NTTMLANISLNATR----------NEENITS------FFTDEEWLAINGT----LPW----IVGF 43

  Fly    89 IFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGS 153
            .||::......||.:|:.:|..:.:||:.||..::||:.|||:...|...|.....:...||:|.
  Fly    44 FFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGR 108

  Fly   154 IYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRK--VRIILVLIWALSCVLSAPC 216
            .:|....::..||...|::|||.:|.||::|:|||::.|..|.:  ..|.:|.:|.:..|:|.|.
  Fly   109 FWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPV 173

  Fly   217 LLYSSIMTKHYYNGKSRT---VCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMG 278
            .....::..  |:.|...   :|.....|...|.:     |.:...:.:|.:|::::...|..|.
  Fly   174 AFTHDVVVD--YDAKKNITYGMCTFTTNDFLGPRT-----YQVTFFISSYLLPLMIISGLYMRMI 231

  Fly   279 RVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIY----AYHNNQVASTK 339
            ..||..   |.......||.:.:::|.|:.:.:|..||..|||..|..:.    ....|.:  ||
  Fly   232 MRLWRQ---GTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTL--TK 291

  Fly   340 YVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHR---FDSPKSRLTN 399
            .|  :.:....||.|::.:|||:|.::::.||..|.:.:.|.    :|::   .|.|..|.|:
  Fly   292 LV--IQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCS----SRYQNYTSDLPPPRKTS 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	80/298 (27%)
		TM helix 1	85..111	CDD:320512	7/25 (28%)
		TM helix 2	118..144	CDD:320512	9/25 (36%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	6/22 (27%)
		TM helix 5	251..280	CDD:320512	5/28 (18%)
		TM helix 6	299..329	CDD:320512	9/33 (27%)
		TM helix 7	342..367	CDD:320512	7/24 (29%)
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	81/302 (27%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	11/29 (38%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	6/33 (18%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	8/26 (31%)