Protein Alignment TkR86C and sNPF-R

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 111/505 - (21%)
• Similarity: 195/505 - (38%)
• Gaps: 156/505 - (30%)

  Fly    85 IWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDW 149
            ::|.:|.|.:|    ||.:|.::|..:|:|:||||.|:.||:::|:|:..|...|..::.....|
  Fly    69 LYATVFVLGVF----GNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGRW 129

  Fly   150 PFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSA 214
            .||...|.:.:|....::..|..||.:|:.|||..|::|...|........|:|.||.::.:.:.
  Fly   130 AFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVIALLATV 194

  Fly   215 PCLLYSSIMTKHYYNGKS----------------------------------------------- 232
            |..:|.. ||....||..
  Fly   195 PYGMYMK-MTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTG 258

  Fly   233 ------RTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSI---- 287
                  |..|...||..:|..     .:..|...|.:.:|..::.|||      :|.|..:
  Fly   259 PEMPYVRVYCEENWPSEQYRK-----VFGAITTTLQFVLPFFIISICY------VWISVKLNQRA 312

  Fly   288 ----GENTDRQMESMKS-KRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLG 347
                |..:.|:.|:.:. |::..||.||:|::|.:.|||.::..|:...:::....::    |:.
  Fly   313 RAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRF----YIL 373

  Fly   348 FYW----LAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTN----KNSSN 404
            |::    :|||:...||.:|.|:|:.||..|:.::.|         |:...:.:.|    .|.|:
  Fly   374 FFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPC---------FNPSNNNIINITRGYNRSD 429

  Fly   405 RHT-------------RGGYTVAHSLPNSSPPTTQTLLAVLAQTLTQPKPQTQLLL--------- 447
            |:|             .||.::.....:.:..|.:|.|           |:.:||:
  Fly   430 RNTCGPRLHHGKGDGGMGGGSLDADDQDENGITQETCL-----------PKEKLLIIPREPTYGN 483

  Fly   448 ---------------------SHHSPHPTQPS---AAETKSQWKRSTMET 473
                                 ..|..|..|||   ..|...:.:|.|.||
  Fly   484 GTGAVSPILSGRGINAALVHGGDHQMHQLQPSHHQQVELTRRIRRRTDET 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	85/354 (24%)
		TM helix 1	85..111	CDD:320512	8/25 (32%)
		TM helix 2	118..144	CDD:320512	9/25 (36%)
		TM helix 3	156..186	CDD:320512	9/29 (31%)
		TM helix 4	197..218	CDD:320512	5/20 (25%)
		TM helix 5	251..280	CDD:320512	6/28 (21%)
		TM helix 6	299..329	CDD:320512	11/30 (37%)
		TM helix 7	342..367	CDD:320512	9/28 (32%)
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	85/354 (24%)
		TM helix 1	65..91	CDD:320331	8/25 (32%)
		TM helix 2	98..123	CDD:320331	9/24 (38%)
		TM helix 3	136..166	CDD:320331	9/29 (31%)
		TM helix 4	177..198	CDD:320331	5/20 (25%)
		TM helix 5	278..307	CDD:320331	8/39 (21%)
		TM helix 6	329..359	CDD:320331	11/29 (38%)
		TM helix 7	372..397	CDD:320331	8/24 (33%)