Protein Alignment TkR86C and oprd1b

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_997920.2
• Gene: oprd1b / 336529
• ZFINID: ZDB-GENE-030131-8473
• Length: 375
• Species: Danio rerio
• Alignment Length: 325
• Identity: 88/325 - (27%)
• Similarity: 160/325 - (49%)
• Gaps: 46/325 - (14%)

  Fly    89 IFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGS 153
            ::.::..|.:.||.:|::.|..:..|:|.||.::.||::||.|.:| ...|.....|...||||.
Zfish    60 LYSVICVVGLVGNVLVMYGVVRYTKMKTATNIYIFNLALADALATS-TLPFQSAKYLMGTWPFGE 123

  Fly   154 IYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRR--KVRIILVLIWALSCVLSAPC 216
            :.|.:...:....:.||:|||..:|.|||||:.||::....|.  |.:||.:.:|.||..:..|.
Zfish   124 LLCKVVIAIDYYNMFTSIFTLTMMSVDRYIAVCHPVRALDFRTPVKAKIINICVWILSSAVGFPV 188

  Fly   217 LLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLM---- 277
            ::.:  :||...:||  |:|.:.:||   |....|....:.:.:..:..|::|:.:||.||
Zfish   189 MVMA--VTKELDSGK--TICMLKFPD---PEWYWDTVTKICVFIFAFVFPVLVITVCYGLMILRL 246

  Fly   278 --GRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKY 340
              .|:|.||:          |..::.|::.||.:.:|:.|.|||.|.|:|.|          .|.
Zfish   247 KSVRLLSGSK----------EKDRNLRRITRMVLVVVAAFIICWTPIHIFII----------VKT 291

  Fly   341 V-----QHMYLGFYW-----LAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKS 395
            |     :::.:...|     |...|:.:||::|.::::.|:..|:.........:.::.|...:|
Zfish   292 VVEIDQKNLLVVACWHLCIALGYMNSSLNPVLYAFLDENFKRCFREFCLPFRTRIEQNSFSKARS 356

  Fly   396  395
            Zfish   357  356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	85/302 (28%)
		TM helix 1	85..111	CDD:320512	5/21 (24%)
		TM helix 2	118..144	CDD:320512	9/25 (36%)
		TM helix 3	156..186	CDD:320512	12/29 (41%)
		TM helix 4	197..218	CDD:320512	7/20 (35%)
		TM helix 5	251..280	CDD:320512	7/34 (21%)
		TM helix 6	299..329	CDD:320512	12/29 (41%)
		TM helix 7	342..367	CDD:320512	6/29 (21%)
oprd1b	NP_997920.2	7tmA_Delta_opioid_R	55..335	CDD:320217	85/302 (28%)
		TM helix 1	56..82	CDD:320217	5/21 (24%)
		TM helix 2	89..115	CDD:320217	9/26 (35%)
		TM helix 3	126..156	CDD:320217	12/29 (41%)
		TM helix 4	168..190	CDD:320217	7/21 (33%)
		TM helix 5	215..245	CDD:320217	7/29 (24%)
		TM helix 6	264..290	CDD:320217	11/35 (31%)
		TM helix 7	303..328	CDD:320217	6/24 (25%)