DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TkR86C and moody

DIOPT Version :9

Sequence 1:	NP_001097741.1	Gene:	TkR86C / 41286	FlyBaseID:	FBgn0004841	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001188534.1	Gene:	moody / 31168	FlyBaseID:	FBgn0025631	Length:	670	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	104/532 - (19%)
Similarity:	193/532 - (36%)	Gaps:	129/532 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 TIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSD 148
            |..|::..|:|.|.|.||.:.:..:.....:|.|...|:::|.|||||..:|...|..:..:...
  Fly    37 TFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCALVLPFQGLRFVQGT 101

  Fly   149 WPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHP--LKRRTSRRKVRIILVLIWALSCV 211
            |..|.:.|.:..|:....:..|:..:..|:.:||:.|.|.  ..|...|..:.:::...|..|..
  Fly   102 WRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITHHGLYARIYKRHWIAVMIAACWLFSYG 166

  Fly   212 LSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSL 276
            :..|.||  ....:..|:.:.:| |.:|..|..:.:...       :.:..:.||.:|::.||:
  Fly   167 MQLPTLL--GEWGRFGYDSRLQT-CSIMTDDHGHSSKTT-------LFITAFVIPCLVIIACYA- 220

  Fly   277 MGRVLW-----------------------------GSRSIGENTD-------------------- 292
              ::.|                             ||.::....:
  Fly   221 --KIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVP 283

  Fly   293 ----------------RQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYV 341
                            |::.:.:::.::.:|.:||...|.:|:||..:..:         :.|.|
  Fly   284 ETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVKV---------ADKNV 339

  Fly   342 QH--MYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGL-----TRHRFDSPKSRLTN 399
            :|  :::..|.|...:|.:||:||..|||::|..::.::.|....|     ..:...|...:..:
  Fly   340 EHPSLHICSYILLYLSACINPIIYVIMNKQYRKAYKTVVFCQPARLLLPFGKTNGASSAAEKWKD 404

  Fly   400 KNSSNRHTR-------GGYTVAHSLPNS----------SPPTTQTLLAVLAQTLTQPKPQTQLLL 447
            ...||.|:|       ||...|.....:          :||..|.     ||.|........|:.
  Fly   405 TGLSNNHSRTIVSQMSGGTGAASGAGTATGTAAVAVMQTPPEVQQ-----AQALEMVSRGPDLIS 464

  Fly   448 SHHSPHP--TQP-----SAAETKSQWKRSTMETQIQQAPVTSSCREQRSAQQQQP-PGSGTNRAA 504
            ..:.|.|  |.|     :|....|.....|:...:::   .:.|..........| |.||.....
  Fly   465 KSNLPQPNVTPPPPSVLTATPNGSNSNSLTLRLPLKK---NNHCYTNSGFNSSTPSPSSGLGIGI 526

  Fly   505 VECIMERPADGS 516
            ....:.||..||
  Fly   527 SSSSIYRPGVGS 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	69/352 (20%)
TkR86C	NP_001097741.1	7tm_1	100..363	CDD:278431	59/331 (18%)
moody	NP_001188534.1	7tm_4	44..>167	CDD:304433	31/122 (25%)
		7tm_1	53..363	CDD:278431	59/331 (18%)
		7tm_4	<310..380	CDD:304433	21/78 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459152
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840