Protein Alignment TkR86C and Qrfpr

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_937842.1
• Gene: Qrfpr / 310327
• RGDID: 728380
• Length: 433
• Species: Rattus norvegicus
• Alignment Length: 442
• Identity: 106/442 - (23%)
• Similarity: 207/442 - (46%)
• Gaps: 92/442 - (20%)

  Fly    77 ELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNF 141
            |||...|..:|:...|:..:|:.||.:|:::||..::||||||.|:.:|:::|||::........
  Rat    39 ELPARAKVAFALAGALIFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTM 103

  Fly   142 IFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRR---TSRRKVRIILV 203
            :..::..|..|:..|.:..||.:..|.|.:.|:..|:.:|:..:|||.|.:   |:||.. .||.
  Rat   104 LQNISDKWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTTRRAF-TILG 167

  Fly   204 LIWALSCVLSAPCLLYSSIMTKH-YYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPM 267
            ::|..:.::.:|......:..|: :...|....|...|     .:.:....|:..|||:.:.:|:
  Rat   168 VVWLAAIIVGSPMWHVQRLEIKYDFLYEKEHICCLEEW-----ASPVHQRIYSTFILVILFLLPL 227

  Fly   268 IVMLICYSLMGRVLWGSRSIGENT------DRQMESM-KSKRKVVRMFIAIVSIFAICWLPYHLF 325
            :|||:.||.:|..||..:.:|:::      .::|..: :.|::.|.|.:.:|::||.||.|:|:.
  Rat   228 VVMLVLYSKIGYELWIKKRVGDSSALQTIHGKEMSKIARKKKRAVIMMVTVVALFAACWAPFHVV 292

  Fly   326 FIYAYHNN--------------QVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQR 376
            .:...::|              .||.|       :||:     |::.||.:|.:||:.|:..|..
  Rat   293 HMMVEYSNFEKEYDDVTIKMVFAVAQT-------IGFF-----NSICNPFVYAFMNENFKKNFLS 345

  Fly   377 IICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRGGYTVAHSLPNSSPPTTQTLLAVLAQTLTQPKP 441
            .:|.|.|                |.||:...:.|        ||.       ::::.:.....:|
  Rat   346 AVCYCIV----------------KESSSPARKPG--------NSG-------ISMMQKRAKLSRP 379

  Fly   442 QTQLLLSHHSPHPTQPSAAETKSQWKRSTMETQIQQAPVTSSCREQRSAQQQ 493
            |          .|.:.:..:|.|.   ::::.::.:.|     ||:|..::|
  Rat   380 Q----------RPVEETKGDTFSD---ASIDVKLCEQP-----REKRQLKRQ 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	82/314 (26%)
		TM helix 1	85..111	CDD:320512	8/25 (32%)
		TM helix 2	118..144	CDD:320512	7/25 (28%)
		TM helix 3	156..186	CDD:320512	8/29 (28%)
		TM helix 4	197..218	CDD:320512	4/20 (20%)
		TM helix 5	251..280	CDD:320512	11/28 (39%)
		TM helix 6	299..329	CDD:320512	10/29 (34%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
Qrfpr	NP_937842.1	7tmA_QRFPR	46..343	CDD:320333	82/314 (26%)
		TM helix 1	47..73	CDD:320333	8/25 (32%)
		TM helix 2	80..106	CDD:320333	7/25 (28%)
		TM helix 3	118..148	CDD:320333	8/29 (28%)
		TM helix 4	161..182	CDD:320333	5/21 (24%)
		TM helix 5	211..236	CDD:320333	9/24 (38%)
		TM helix 6	266..296	CDD:320333	10/29 (34%)
		TM helix 7	311..336	CDD:320333	9/36 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	356..389		7/57 (12%)