Protein Alignment TkR86C and npy4r

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_571515.1
• Gene: npy4r / 30717
• ZFINID: ZDB-GENE-980526-393
• Length: 377
• Species: Danio rerio
• Alignment Length: 354
• Identity: 93/354 - (26%)
• Similarity: 171/354 - (48%)
• Gaps: 36/354 - (10%)

  Fly    42 SLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELP-WEQKTI---WAIIFGLMMFVAIAGNG 102
            :||:|.:.:..:..|:     ||           .::| |:..|:   ..:.:.|::.:.:.||.
Zfish    13 ALLNSTLTHNQSNSSL-----FL-----------LDVPCWQSSTMTLTLVLCYCLVLILGLLGNI 61

  Fly   103 IVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTV 167
            :::.|:...|....||:..:.|||::|:|:|.....|..::.|...|.||::.|.:..||..|:|
Zfish    62 LLICIIMHQRDPPNVTSILIANLSVSDILVSVFCLPFTVVYTLMDHWIFGALLCRLMPFVQCVSV 126

  Fly   168 STSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYN--- 229
            :.||.:||.|:.:|:..|:||...:.|..:..|.::.:|.|:||.|.|.|.: .::|...|:
Zfish   127 TVSVLSLVLIALERHQLILHPSGWKPSVPQAYIAVLTVWLLACVTSLPFLAF-HLLTSEPYSLFP 190

  Fly   230 --GKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICY-----SLMGRVLWGSRSI 287
              .....||..:||...:     ..||...:|:..|..|:::||:||     .|..|.....|..
Zfish   191 APLSQLQVCLEVWPSQDH-----KLAYTTSLLLFQYCCPLLLMLLCYLRIFLRLQRRERMLERQC 250

  Fly   288 GENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGFYWLA 352
            ..|.:.:...:...:::..|...:|:.||:||||.:.|.:.|..:.:|........::...:.||
Zfish   251 SRNREDEHRRVMHSKRINVMLATLVAAFAVCWLPLNAFNVVADCDQEVLPVCNHNLLFSLCHLLA 315

  Fly   353 MSNAMVNPLIYYWMNKRFRMYFQRIICCC 381
            ||:..|||:||.::|..||.....::..|
Zfish   316 MSSTCVNPIIYGFLNSNFRKDVASVVLHC 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	84/302 (28%)
		TM helix 1	85..111	CDD:320512	4/28 (14%)
		TM helix 2	118..144	CDD:320512	8/25 (32%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	7/20 (35%)
		TM helix 5	251..280	CDD:320512	10/33 (30%)
		TM helix 6	299..329	CDD:320512	9/29 (31%)
		TM helix 7	342..367	CDD:320512	9/24 (38%)
npy4r	NP_571515.1	7tm_GPCRs	43..337	CDD:475119	83/299 (28%)
		TM helix 1	45..69	CDD:320519	4/23 (17%)
		TM helix 2	78..100	CDD:320519	7/21 (33%)
		TM helix 3	116..138	CDD:320519	9/21 (43%)
		TM helix 4	159..175	CDD:320519	6/15 (40%)
		TM helix 5	210..233	CDD:320519	8/22 (36%)
		TM helix 6	268..290	CDD:320519	9/21 (43%)
		TM helix 7	305..330	CDD:320519	9/24 (38%)