Protein Alignment TkR86C and oprd1a

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_571333.2
• Gene: oprd1a / 30509
• ZFINID: ZDB-GENE-990415-199
• Length: 374
• Species: Danio rerio
• Alignment Length: 393
• Identity: 114/393 - (29%)
• Similarity: 187/393 - (47%)
• Gaps: 68/393 - (17%)

  Fly    46 SIIDNRD--NLESINE-----AKDFLTECLFPSPTRPYELPWEQKTIWAII--------FGLMMF 95
            |:|...|  :|.|||.     ..|.|:   |....|.|..|...|:...||        :.::..
Zfish     4 SVIPGADIPDLYSINPFNVTFPDDVLS---FVPDGRNYTEPNPVKSPAGIIIAISITALYSVICV 65

  Fly    96 VAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINN 160
            |.:.||.:|::.|..:..::|.||.::.||::||.|.:|.....:..:::|: ||||.:.|.:..
Zfish    66 VGLLGNILVMYGVVRYTKLKTATNIYIFNLALADALATSTLPFQSTKYLMNT-WPFGELLCKVVI 129

  Fly   161 FVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRR--KVRIILVLIWALSCVLSAPCLLYSSIM 223
            .:....:.||:|||..:|.|||||:.||::....|.  |.:||.|.||.||..:..|.:    ||
Zfish   130 AIDYYNMFTSIFTLTMMSVDRYIAVCHPVRALEFRTPIKAKIINVCIWILSSAVGVPIM----IM 190

  Fly   224 TKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLM------GRVLW 282
            .......::.|||.:.:||   |....|....:.:.:..:.:|::|:.|||.||      .|:|.
Zfish   191 AVTRVTNQNTTVCMLKFPD---PDWYWDTVTKICVFIFAFVVPVLVITICYGLMILRLKSVRLLS 252

  Fly   283 GSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIY--AYHNNQ-----VASTKY 340
            ||:    ..||.|      |::.||.:.:|:.|.|||.|.|:|.|.  ....||     :||
Zfish   253 GSK----EKDRNM------RRITRMVLVVVAAFIICWTPIHIFIIVKTLVDINQKNPFVIAS--- 304

  Fly   341 VQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNR 405
             .|:.:.   |..:|:.:||::|.::::.|:..|:..    |:.. |.|.|.     :|.|.:..
Zfish   305 -WHLCIA---LGYTNSSLNPVLYAFLDENFKRCFRDF----CLPF-RTRADQ-----SNLNRARN 355

  Fly   406 HTR 408
            .||
Zfish   356 ATR 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	91/312 (29%)
		TM helix 1	85..111	CDD:320512	7/33 (21%)
		TM helix 2	118..144	CDD:320512	8/25 (32%)
		TM helix 3	156..186	CDD:320512	12/29 (41%)
		TM helix 4	197..218	CDD:320512	9/20 (45%)
		TM helix 5	251..280	CDD:320512	8/34 (24%)
		TM helix 6	299..329	CDD:320512	12/31 (39%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
oprd1a	NP_571333.2	7tmA_Delta_opioid_R	54..334	CDD:320217	89/304 (29%)
		TM helix 1	55..81	CDD:320217	5/25 (20%)
		TM helix 2	88..114	CDD:320217	8/25 (32%)
		TM helix 3	125..155	CDD:320217	12/29 (41%)
		TM helix 4	167..189	CDD:320217	9/25 (36%)
		TM helix 5	214..244	CDD:320217	8/29 (28%)
		TM helix 6	263..289	CDD:320217	11/25 (44%)
		TM helix 7	302..327	CDD:320217	8/31 (26%)