Protein Alignment TkR86C and Npy1r

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001106828.1
• Gene: Npy1r / 29358
• RGDID: 3198
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 391
• Identity: 110/391 - (28%)
• Similarity: 188/391 - (48%)
• Gaps: 35/391 - (8%)

  Fly    42 SLLSSIIDNRDNLESINEAKDFLT----ECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNG 102
            |.|.|.::|.....:::|...||.    :|         .||.......|:.:|.::.:.::||.
  Rat     3 STLFSRVENYSVHYNVSENSPFLAFENDDC---------HLPLAVIFTLALAYGAVIILGVSGNL 58

  Fly   103 IVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTV 167
            .::.|:...:.||.|||..::|||.:|||::.:...|.|::.|...|.||...|.:|.||..|::
  Rat    59 ALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSI 123

  Fly   168 STSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYN--- 229
            :.|:|:||.|:.:|:..|::|...|.:.|...|.:.:||.|:...|.|.::|..:..:.:.|
  Rat   124 TVSIFSLVLIAVERHQLIINPRGWRPNNRHAYIGITVIWVLAVASSLPFVIYQILTDEPFQNVSL 188

  Fly   230 --GKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICY-SLMGRVLWGSRSIGENT 291
              .|.:.|||     .::|:.....:|..::|||.|..|:..:.||| .:..|:...:..:.:..
  Rat   189 AAFKDKYVCF-----DKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYVRLKRRNNMMDKIR 248

  Fly   292 DRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNA 356
            |.:..|.::||..| |.::||..||:||||..:|......|:|:.:|.....::|..:..||.:.
  Rat   249 DSKYRSSETKRINV-MLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMIST 312

  Fly   357 MVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRGGYTVAHSLPNSS 421
            .|||:.|.::||.|:...|.....|       .|.|..........|..||....|   ||..:|
  Rat   313 CVNPIFYGFLNKNFQRDLQFFFNFC-------DFRSRDDDYETIAMSTMHTDVSKT---SLKQAS 367

  Fly   422 P 422
            |
  Rat   368 P 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	88/295 (30%)
		TM helix 1	85..111	CDD:320512	5/25 (20%)
		TM helix 2	118..144	CDD:320512	10/25 (40%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	9/29 (31%)
		TM helix 6	299..329	CDD:320512	13/29 (45%)
		TM helix 7	342..367	CDD:320512	7/24 (29%)
Npy1r	NP_001106828.1	7tmA_NPY1R	40..330	CDD:320517	88/295 (30%)
		TM helix 1	41..67	CDD:320517	5/25 (20%)
		TM helix 2	74..99	CDD:320517	10/24 (42%)
		TM helix 3	112..142	CDD:320517	11/29 (38%)
		TM helix 4	153..174	CDD:320517	6/20 (30%)
		TM helix 5	207..236	CDD:320517	9/28 (32%)
		TM helix 6	255..285	CDD:320517	13/30 (43%)
		TM helix 7	298..323	CDD:320517	7/24 (29%)