Protein Alignment TkR86C and GPR33

DIOPT Version :9

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001184113.2
• Gene: GPR33 / 2856
• HGNCID: 4489
• Length: 333
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 83/383 - (21%)
• Similarity: 150/383 - (39%)
• Gaps: 111/383 - (28%)

  Fly    35 LNRTEVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIA 99
            :|.|:.:...|:::.|.             |:.|.|:          .|.|.|:...:...:...
Human     4 INSTDYLINASTLVRNS-------------TQFLAPA----------SKMIIALSLYISSIIGTI 45

  Fly   100 GNGIVLWIVTGHRSMRTVT---------NYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIY 155
            .||:.||::. .:..:||.         :||:..:.:..:..|.|.         ::.|.||:..
Human    46 TNGLYLWVLR-FKMKQTVNTLLFFHLILSYFISTMILPFMATSQLQ---------DNHWNFGTAL 100

  Fly   156 CTINNFVANVTVSTSVFTLVAISFDRYIAIVHPL---KRRTSRRKVRIILVLIWALSCVLSAPCL 217
            |.:.|...::.:.||||.|.||..|||:..:||:   :.||.|....|:|. :|..:..||.|.|
Human   101 CKVFNGTLSLGMFTSVFFLSAIGLDRYLLTLHPVWSQQHRTPRWASSIVLG-VWISAAALSIPYL 164

  Fly   218 LYSSIMTKHYYNGK--------------------SR----TVCFMMWPDGRYPTSMADYAYNLII 258
            ::..  |.|...||                    ||    ..||:    .|:
Human   165 IFRE--THHDRKGKVTCQNNYAVSTNWESKEMQASRQWIHVACFI----SRF------------- 210

  Fly   259 LVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYH 323
             :|.:.:|..:::.||         .|...:..:|.:  .||.:....|..||:|.| :||:|||
Human   211 -LLGFLLPFFIIIFCY---------ERVASKVKERSL--FKSSKPFKVMMTAIISFF-VCWMPYH 262

  Fly   324 LFFIYAYHNNQVASTKYVQHMYLGFYWLAMS---NAMVNPLIYYWMNKRFRMYFQRII 378
            :      |...:.:|.....:.|......::   |.:.:|.:|.::.:.|:..|::.|
Human   263 I------HQGLLLTTNQSLLLELTLILTVLTTSFNTIFSPTLYLFVGENFKKVFKKSI 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	72/322 (22%)
		7tm_1	100..363	CDD:278431	69/301 (23%)
GPR33	NP_001184113.2	7tm_1	47..265	CDD:278431	64/266 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910