DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TkR86C and OXGR1

DIOPT Version :9

Sequence 1:	NP_001097741.1	Gene:	TkR86C / 41286	FlyBaseID:	FBgn0004841	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001333123.1	Gene:	OXGR1 / 27199	HGNCID:	4531	Length:	337	Species:	Homo sapiens

Alignment Length:	359	Identity:	85/359 - (23%)
Similarity:	151/359 - (42%)	Gaps:	81/359 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 INEAKDFLTECL-FPS-------------PTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWI 107
            :||..|:|.... ||.             |.:.:.||        :|:|::..|...||.:|  |
Human     1 MNEPLDYLANASDFPDYAAAFGNCTDENIPLKMHYLP--------VIYGIIFLVGFPGNAVV--I 55

  Fly   108 VTGHRSMR--TVTNYFLLNLSIADLL-MSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVST 169
            .|....||  ..:...:|||:..||| ::||..:.:: :....:|.||...|....|..:..:.:
Human    56 STYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHY-YASGENWIFGDFMCKFIRFSFHFNLYS 119

  Fly   170 SVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILV---LIWALSCVLSAPC--LLYSSIMTKHYYN 229
            |:..|...|..||..|:||:. ..|..|.|..:|   ::|.:|.|...|.  |:.|:       |
Human   120 SILFLTCFSIFRYCVIIHPMS-CFSIHKTRCAVVACAVVWIISLVAVIPMTFLITST-------N 176

  Fly   230 GKSRTVCF----------MMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGS 284
            ..:|:.|.          :.|             ||||:...|:.:|::::.:||:.:...|
Human   177 RTNRSACLDLTSSDELNTIKW-------------YNLILTATTFCLPLVIVTLCYTTIIHTL--- 225

  Fly   285 RSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVAST----KYVQHMY 345
             :.|..||..:     |:|..|:.|.::..|.:|:||:|:..:....:..::.:    ..:...|
Human   226 -THGLQTDSCL-----KQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLSISCSIENQIHEAY 284

  Fly   346 LGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIIC 379
            :....||..|...|.|:|..::..    ||:.:|
Human   285 IVSRPLAALNTFGNLLLYVVVSDN----FQQAVC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	72/305 (24%)
TkR86C	NP_001097741.1	7tm_1	100..363	CDD:278431	69/284 (24%)
OXGR1	NP_001333123.1	7tmA_OXGR1	34..313	CDD:320497	77/323 (24%)
		TM helix 1	34..61	CDD:320497	10/36 (28%)
		TM helix 2	68..93	CDD:320497	8/25 (32%)
		TM helix 3	106..136	CDD:320497	7/29 (24%)
		TM helix 4	148..170	CDD:320497	6/21 (29%)
		TM helix 5	195..224	CDD:320497	9/41 (22%)
		TM helix 6	234..264	CDD:320497	9/34 (26%)
		TM helix 7	281..306	CDD:320497	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910