Protein Alignment TkR86C and Npy5r

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_037001.1
• Gene: Npy5r / 25340
• RGDID: 3199
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 444
• Identity: 81/444 - (18%)
• Similarity: 158/444 - (35%)
• Gaps: 137/444 - (30%)

  Fly    61 KDFLTE--------CLFPSPTRPYELPWEQ-----KTIWAIIFGLMMFVAI---AGNGIVLWIVT 109
            |.|:||        ..||:        ||.     ..:...:.||..||::   .||.::|..|.
  Rat    11 KTFVTENNTAAARNAAFPA--------WEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVM 67

  Fly   110 GHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTL 174
            ..|:.:|..|:.:.||:.:|:|:......|....:|...|.||...|.|..|:..|:|..|...|
  Rat    68 KKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLIL 132

  Fly   175 VAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIM-TKHYYNG---KSRTV 235
            ::|:..||..|.||:....:......::..:|.|...:.:|..::.|:: .|..:..   .|:.:
  Rat   133 ISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYL 197

  Fly   236 CFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQME---- 296
            |...||...|     ..|:.:.:|::.|.:|::.:.:.::.:.|.:....|..||...:.|
  Rat   198 CVESWPSDSY-----RIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINL 257

  Fly   297 ----------------------------------------------------------------- 296
                                                                             
  Rat   258 TLQPSKKSRNQAKTPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQGKHLAVPENPASVRSQL 322

  Fly   297 -------------------------SMKSKRKVVRM----------FIAIVSIFAICWLPYHLFF 326
                                     .|:.||.:.|:          ...::.:||:.|:|.|:|.
  Rat   323 SPSSKVIPGVPICFEVKPEESSDAHEMRVKRSITRIKKRSRSVFYRLTILILVFAVSWMPLHVFH 387

  Fly   327 IYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICC 380
            :....|:.:.|.::.:.:|...:.|.|.:..:||::|.::|...:...:.:|.|
  Rat   388 VVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	71/400 (18%)
		TM helix 1	85..111	CDD:320512	8/28 (29%)
		TM helix 2	118..144	CDD:320512	6/25 (24%)
		TM helix 3	156..186	CDD:320512	10/29 (34%)
		TM helix 4	197..218	CDD:320512	3/20 (15%)
		TM helix 5	251..280	CDD:320512	4/28 (14%)
		TM helix 6	299..329	CDD:320512	9/39 (23%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
Npy5r	NP_037001.1	7tmA_NPY5R	42..435	CDD:320520	71/397 (18%)
		TM helix 1	43..69	CDD:320520	8/25 (32%)
		TM helix 2	76..101	CDD:320520	6/24 (25%)
		TM helix 3	114..144	CDD:320520	10/29 (34%)
		TM helix 4	155..176	CDD:320520	3/20 (15%)
		TM helix 5	208..237	CDD:320520	4/28 (14%)
		TM helix 6	360..390	CDD:320520	6/29 (21%)
		TM helix 7	403..428	CDD:320520	6/24 (25%)