Protein Alignment TkR86C and Oprd1

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_036749.1
• Gene: Oprd1 / 24613
• RGDID: 3233
• Length: 372
• Species: Rattus norvegicus
• Alignment Length: 326
• Identity: 84/326 - (25%)
• Similarity: 157/326 - (48%)
• Gaps: 38/326 - (11%)

  Fly    89 IFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGS 153
            ::..:..|.:.||.:|::.:..:..::|.||.::.||::||.|.:| ...|.....|...||||.
  Rat    55 LYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATS-TLPFQSAKYLMETWPFGE 118

  Fly   154 IYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSR--RKVRIILVLIWALSCVLSAPC 216
            :.|.....:....:.||:|||..:|.|||||:.||:|....|  .|.::|.:.||.|:..:..|.
  Rat   119 LLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPI 183

  Fly   217 LLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLM---- 277
            ::.:....:     ....||.:.:|.   |:...|....:.:.:..:.:|::::.:||.||
  Rat   184 MVMAVTQPR-----DGAVVCTLQFPS---PSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL 240

  Fly   278 --GRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFI---YAYHNNQVAS 337
              .|:|.||:          |..:|.|::.||.:.:|..|.:||.|.|:|.|   ....|.:...
  Rat   241 RSVRLLSGSK----------EKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPL 295

  Fly   338 TKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVG-----LTRHRFDSPKSRL 397
            .....|:.:.   |..:|:.:||::|.::::.|:..|:::....|.|     |.|.|..:.:.|:
  Rat   296 VVAALHLCIA---LGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERV 357

  Fly   398 T 398
            |
  Rat   358 T 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	76/295 (26%)
		TM helix 1	85..111	CDD:320512	4/21 (19%)
		TM helix 2	118..144	CDD:320512	9/25 (36%)
		TM helix 3	156..186	CDD:320512	12/29 (41%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	6/34 (18%)
		TM helix 6	299..329	CDD:320512	12/32 (38%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
Oprd1	NP_036749.1	7tmA_Delta_opioid_R	50..329	CDD:320217	76/295 (26%)
		TM helix 1	51..77	CDD:320217	4/21 (19%)
		TM helix 2	84..110	CDD:320217	9/26 (35%)
		TM helix 3	121..151	CDD:320217	12/29 (41%)
		TM helix 4	163..185	CDD:320217	6/21 (29%)
		TM helix 5	209..239	CDD:320217	6/29 (21%)
		TM helix 6	258..284	CDD:320217	10/25 (40%)
		TM helix 7	297..322	CDD:320217	6/27 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..372		5/19 (26%)