Protein Alignment TkR86C and Pgr15l

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001028533.1
• Gene: Pgr15l / 245526
• MGIID: 2676330
• Length: 456
• Species: Mus musculus
• Alignment Length: 353
• Identity: 95/353 - (26%)
• Similarity: 180/353 - (50%)
• Gaps: 30/353 - (8%)

  Fly    39 EVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPT---------RPYELPWEQKTIWAIIFGLMM 94
            |.:|.:.||.|...|..:.|...  ::...:..||         .|:.:   .|.:....:.:::
Mouse    24 ENISWVPSIEDQSCNHTTQNGTN--ISSAEWGGPTGSVRRWLGGNPHIM---AKIVLTFAYAVII 83

  Fly    95 FVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTIN 159
            .:::.||.:|..:...|:.::..|...:.||:|:|:|:..||..|.....|:..|.||.|.|.::
Mouse    84 VISLFGNSLVCQVFVKHKEIKKSTGLLIFNLAISDILIILLNSPFALARFLSGQWVFGRIMCHVS 148

  Fly   160 NFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMT 224
            .|....::..|..||:|::.||:..|:||:|.|.:..:...::.:||:::..|:.|..:|.::.|
Mouse   149 RFAQYCSLHVSTLTLMAVAMDRHRVILHPMKPRLTHSQCLFVVAMIWSIAVFLALPHAIYQNLFT 213

  Fly   225 KHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGE 289
            ....:|.:|:.|...:|.   |:.:.....:|...:|.|.:|::|:::.||.:|:.||...:||:
Mouse   214 LVNMDGDTRSYCLPSFPG---PSILVSKYVDLGTFILLYILPLLVIVVTYSHLGKRLWIQNAIGD 275

  Fly   290 NTDRQ-MESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIY----AYHNNQVASTKYVQHMYLGFY 349
            .:.|| |...:.::|.:||.|.||.:||:||.|.:.:.:.    ...|:.|        ::..|:
Mouse   276 ASARQLMAHYQKRKKSIRMLILIVLVFAVCWFPLNFYVVLISSAGVENDSV--------LFYAFH 332

  Fly   350 WLAMSNAMVNPLIYYWMNKRFRMYFQRI 377
            |.|||:...||.||.|:|:.||...:.|
Mouse   333 WFAMSSTCYNPFIYCWLNRSFRAKLRSI 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	83/294 (28%)
		TM helix 1	85..111	CDD:320512	3/25 (12%)
		TM helix 2	118..144	CDD:320512	9/25 (36%)
		TM helix 3	156..186	CDD:320512	8/29 (28%)
		TM helix 4	197..218	CDD:320512	4/20 (20%)
		TM helix 5	251..280	CDD:320512	8/28 (29%)
		TM helix 6	299..329	CDD:320512	11/33 (33%)
		TM helix 7	342..367	CDD:320512	10/24 (42%)
Pgr15l	NP_001028533.1	7tmA_GPR83	73..357	CDD:320511	83/294 (28%)
		TM helix 1	74..100	CDD:320511	3/25 (12%)
		TM helix 2	107..132	CDD:320511	9/24 (38%)
		TM helix 3	145..175	CDD:320511	8/29 (28%)
		TM helix 4	186..207	CDD:320511	4/20 (20%)
		TM helix 5	237..266	CDD:320511	8/28 (29%)
		TM helix 6	286..316	CDD:320511	11/29 (38%)
		TM helix 7	325..350	CDD:320511	11/32 (34%)