Protein Alignment TkR86C and Npbwr1

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_034472.1
• Gene: Npbwr1 / 226304
• MGIID: 891989
• Length: 329
• Species: Mus musculus
• Alignment Length: 319
• Identity: 90/319 - (28%)
• Similarity: 158/319 - (49%)
• Gaps: 20/319 - (6%)

  Fly    67 CLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLL 131
            |...|...|..||........:::|::..|.:|||..||:::.....|:||||.|:|||:|||.|
Mouse    23 CPNGSSLAPLPLPQPLAVAVPVVYGVICAVGLAGNSAVLYVLLRTPRMKTVTNVFILNLAIADEL 87

  Fly   132 MSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLK-RRTSR 195
            . :|....|....|...||||.:.|.:...|......:|::.|..:|.|||:.::...: ||.|.
Mouse    88 F-TLVLPINIADFLLRRWPFGEVMCKLIVAVDQYNTFSSLYFLAVMSADRYLVVLATAESRRVSG 151

  Fly   196 R---KVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLI 257
            |   ..|.:.:.:|||..::..|..:::.:..:     :.|..|.:::|.   |.:....|..|.
Mouse   152 RTYGAARAVSLAVWALVTLVVLPFAVFARLDEE-----QGRRQCVLVFPQ---PEAFWWRASRLY 208

  Fly   258 ILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESM-KSKRKVVRMFIAIVSIFAICWLP 321
            .|||.:.||  |..|| :|...:|...|:|  ..|...::: ::|::|..:..||:::..:||.|
Mouse   209 TLVLGFAIP--VTTIC-ALYTTLLCRLRAI--QLDSHAKALDRAKKRVTLLVAAILAVCLLCWTP 268

  Fly   322 YHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICC 380
            |||..|.|. ...:..|..|..:......|:.:|:.:||.:|.:::..||...::::.|
Mouse   269 YHLSTIVAL-TTDLPQTPLVIGISYFITSLSYANSCLNPFLYAFLDDSFRRSLRQLVSC 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	84/294 (29%)
		TM helix 1	85..111	CDD:320512	7/25 (28%)
		TM helix 2	118..144	CDD:320512	12/25 (48%)
		TM helix 3	156..186	CDD:320512	8/29 (28%)
		TM helix 4	197..218	CDD:320512	5/20 (25%)
		TM helix 5	251..280	CDD:320512	11/28 (39%)
		TM helix 6	299..329	CDD:320512	11/29 (38%)
		TM helix 7	342..367	CDD:320512	5/24 (21%)
Npbwr1	NP_034472.1	7tmA_NPBWR	40..320	CDD:320215	84/294 (29%)
		TM helix 1	41..67	CDD:320215	7/25 (28%)
		TM helix 2	74..100	CDD:320215	12/26 (46%)
		TM helix 3	111..141	CDD:320215	8/29 (28%)
		TM helix 4	155..177	CDD:320215	5/21 (24%)
		TM helix 5	202..231	CDD:320215	12/31 (39%)
		TM helix 6	246..276	CDD:320215	11/29 (38%)
		TM helix 7	288..313	CDD:320215	5/24 (21%)