DRSC/TRiP Functional Genomics Resources

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Protein Alignment TkR86C and P2ry10b

DIOPT Version :9

Sequence 1:NP_001097741.1 Gene:TkR86C / 41286 FlyBaseID:FBgn0004841 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_001116067.1 Gene:P2ry10b / 213438 MGIID:2441814 Length:352 Species:Mus musculus


Alignment Length:324 Identity:71/324 - (21%)
Similarity:139/324 - (42%) Gaps:52/324 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 QKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLN 146
            |.:::|..:..:....:..|.:.||::....|.:.....|::|||:|| |...|:......:.:|
Mouse    21 QYSLYATTYIFIFIPGLLANSVALWVLCRFISKKNKAIIFMINLSVAD-LAHVLSLPLRIYYYIN 84

  Fly   147 SDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRI-ILVLIWAL-- 208
            ..|||....|.:..::..:.:..|:|.|..||..|.:.::.|.:.|..:|:..: |...:|.:  
Mouse    85 RHWPFQRALCLLCFYLKYLNMYASIFFLTCISLQRCLFLLKPFRARNWKRRYDVAISAAVWIIVG 149

  Fly   209 SCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYG--------- 264
            :..|..|.|..:.:..    |.:|   ||            ||.....|.:..:.|         
Mouse   150 TACLPLPILRSAGLAN----NSES---CF------------ADLGLQDITMASSIGMVTAAELGG 195

  Fly   265 --IPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFI 327
              :|::::..|       .|.:|...:......:::|.::|.:||.:....:|.:|:.||||.|.
Mouse   196 FVLPVVIITYC-------TWKTRKSLQEFQDPPQNIKERKKALRMVLMCAVVFIVCFTPYHLNFP 253

  Fly   328 YAYHNNQ--VASTKYVQHMYLGFY----WLAMSNAMVNPLIYYWMNKRFRMYFQR----IICCC 381
            :.....|  .::..::::. |.|:    .||..|..::|::||:|...||..|..    :|..|
Mouse   254 FFMMVKQRVFSNCSFIRNT-LCFHIISLCLANLNCCLDPVVYYFMTSEFRDQFSEHGNLVIQSC 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TkR86CNP_001097741.1 7tm_4 92..376 CDD:304433 67/303 (22%)
7tm_1 100..363 CDD:278431 61/282 (22%)
P2ry10bNP_001116067.1 7tm_GPCRs 23..304 CDD:421689 67/308 (22%)
TM helix 1 23..50 CDD:410628 4/26 (15%)
TM helix 2 57..82 CDD:410628 8/25 (32%)
TM helix 3 94..124 CDD:410628 7/29 (24%)
TM helix 4 135..157 CDD:410628 3/21 (14%)
TM helix 5 184..213 CDD:410628 5/35 (14%)
TM helix 6 225..255 CDD:410628 11/29 (38%)
TM helix 7 273..298 CDD:410628 8/24 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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