Protein Alignment TkR86C and npr-7

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_509570.3
• Gene: npr-7 / 185321
• WormBaseID: WBGene00018067
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 355
• Identity: 88/355 - (24%)
• Similarity: 164/355 - (46%)
• Gaps: 51/355 - (14%)

  Fly    53 NLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTV 117
            |::|  ...||  :|.:|:    .::....||:.|:.:||:..:::.||..||.||...|.|:||
 Worm     2 NIDS--NLTDF--QCEYPA----IDIGIHMKTLLAVGYGLVGALSLVGNLAVLLIVICRREMQTV 58

  Fly   118 TNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRY 182
            ||.|:.::|.|||:::|.:.....:......|.||...|.:.:.:..:::.....||.|::.|||
 Worm    59 TNIFISSVSAADLVITSFSLWATPLAYYQRVWHFGKYMCYMVSIIQGLSLMWVPLTLAAVALDRY 123

  Fly   183 IAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCL----LYSSIMTKHYYNGKSRTVCFMMWPDG 243
            ..:..|.::..|::...:|:..||.....:.:|.:    ...|....|:        |...|...
 Worm   124 SLVASPFRQPMSKKTCLLIIAGIWMGGFAVLSPMIRMVDFVDSYGPCHF--------CLESWDHD 180

  Fly   244 RYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMG----------RVLWGSRSIGENTDRQMESM 298
            :....:   .|.|.:||:...||::::.:|:..:.          :.|..:.::.::||     :
 Worm   181 KQHYRL---FYGLSVLVIRSAIPLVLISLCHWRIAVILNTQTKKFQTLRSASTVTQSTD-----I 237

  Fly   299 KSKRKVVRMFIAIVSIFAICWLPYHLF-----FIYAYHNNQVASTKYVQHMYLGF-YWLAMSNAM 357
            :.|:::..:.:|:|.|||:..||..|.     .|..|....|...  |:|....| :|.||:..:
 Worm   238 RRKQRLQTLLLAMVVIFAVSSLPLDLSNVLQDLIVVYQVRPVPDN--VRHFIFFFCHWTAMAGTL 300

  Fly   358 VNPLIYYWMNKRFRMYFQRIICCCCVGLTR 387
            :|||:|.:.|:.||...|     .|.|..|
 Worm   301 LNPLVYAYYNENFRRQIQ-----TCFGEMR 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	77/309 (25%)
		TM helix 1	85..111	CDD:320512	9/25 (36%)
		TM helix 2	118..144	CDD:320512	8/25 (32%)
		TM helix 3	156..186	CDD:320512	7/29 (24%)
		TM helix 4	197..218	CDD:320512	4/24 (17%)
		TM helix 5	251..280	CDD:320512	7/38 (18%)
		TM helix 6	299..329	CDD:320512	10/34 (29%)
		TM helix 7	342..367	CDD:320512	9/25 (36%)
npr-7	NP_509570.3	7tmA_NPYR-like	25..317	CDD:320331	77/309 (25%)
		TM helix 1	26..52	CDD:320331	9/25 (36%)
		TM helix 2	59..84	CDD:320331	8/24 (33%)
		TM helix 3	97..127	CDD:320331	7/29 (24%)
		TM helix 4	138..159	CDD:320331	4/20 (20%)
		TM helix 5	185..214	CDD:320331	7/31 (23%)
		TM helix 6	238..268	CDD:320331	9/29 (31%)
		TM helix 7	285..310	CDD:320331	9/24 (38%)