Protein Alignment TkR86C and npr-3

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_502162.1
• Gene: npr-3 / 182494
• WormBaseID: WBGene00007006
• Length: 376
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 94/328 - (28%)
• Similarity: 162/328 - (49%)
• Gaps: 24/328 - (7%)

  Fly    83 KTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNF----IF 143
            :.|:::::.|:...||.||.:||:::|.::...:|...|:..|:.:||||    |:|:.    |.
 Worm    25 RAIFSLLYLLVWVGAIVGNTLVLYVLTFNQVSLSVRTVFVGCLAGSDLLM----CLFSLPITAIS 85

  Fly   144 MLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWAL 208
            :.:..|.|.:|:|.:.......|:..|.|||..|:.||.:.|:.|.:...:..:...|:..||.|
 Worm    86 IFSRVWVFPAIFCKLIGVFQGGTIFVSSFTLTVIALDRCVLILRPNQEIVNFPRAVFIVFCIWLL 150

  Fly   209 SCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADY--AYNLIILVLTYGIPMIVML 271
            ...|:.|..:||.|..   |:....|.|...|||....|..:..  ||.|.:|||.:|||.::..
 Worm   151 GYSLALPVGIYSDIAV---YDEICGTFCEENWPDFNPDTGRSGIRRAYGLSVLVLQFGIPALISS 212

  Fly   272 ICYSLMGRVLWG--SRSIGENTDRQMES--MKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHN 332
            |||.::.||:..  :|..|.|...:.|:  :..|.:..||.|.:|..|.:.|:|::...:|   .
 Worm   213 ICYWMISRVMSDQLARRRGHNIRPESETKLVNRKTRANRMMIVMVVGFVLAWMPFNAVNLY---R 274

  Fly   333 NQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRL 397
            :....:|:...::...:..||.:|::||:||.|.|.:||    :.|.....|....|....|.:.
 Worm   275 DLFGISKWYSTVFALCHVCAMCSAVLNPIIYSWFNPQFR----QSITTLFKGTDEARLIKKKPQS 335

  Fly   398 TNK 400
            |:|
 Worm   336 TSK 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	88/299 (29%)
		TM helix 1	85..111	CDD:320512	9/25 (36%)
		TM helix 2	118..144	CDD:320512	9/29 (31%)
		TM helix 3	156..186	CDD:320512	9/29 (31%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	12/30 (40%)
		TM helix 6	299..329	CDD:320512	8/29 (28%)
		TM helix 7	342..367	CDD:320512	8/24 (33%)
npr-3	NP_502162.1	7tmA_NPYR-like	26..314	CDD:320331	88/301 (29%)
		TM helix 1	27..53	CDD:320331	9/25 (36%)
		TM helix 2	60..85	CDD:320331	8/28 (29%)
		TM helix 3	98..128	CDD:320331	9/29 (31%)
		TM helix 4	139..160	CDD:320331	6/20 (30%)
		TM helix 5	192..221	CDD:320331	12/28 (43%)
		TM helix 6	244..274	CDD:320331	9/32 (28%)
		TM helix 7	284..309	CDD:320331	8/24 (33%)