Protein Alignment TkR86C and Npy5r

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_057917.2
• Gene: Npy5r / 18168
• MGIID: 108082
• Length: 466
• Species: Mus musculus
• Alignment Length: 403
• Identity: 72/403 - (17%)
• Similarity: 150/403 - (37%)
• Gaps: 116/403 - (28%)

  Fly    89 IFGLMMFVAI---AGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWP 150
            :.||..||::   .||.::|..|...|:.:|..|:.:.||:.:|:|:......|....:|...|.
Mouse    65 LIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWM 129

  Fly   151 FGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAP 215
            ||...|.|..|:..|:|..|...|::|:..||..|.||:....:......::..:|.|...:.:|
Mouse   130 FGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSP 194

  Fly   216 CLLYSSIM-TKHYYNG---KSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSL 276
            ..::.|:: .|..:..   .|:.:|...||...|     ..|:.:.:|::.|.:|::.:.:.::.
Mouse   195 LPVFHSLVELKETFGSALLSSKYLCVESWPSDSY-----RIAFTISLLLVQYILPLVCLTVSHTS 254

  Fly   277 MGRVL--------------------------------------WGSRSI---------------- 287
            :.|.:                                      |....|
Mouse   255 VCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLP 319

  Fly   288 ---GENTDRQM-------------------------------------ESMKSKRKVVRM----- 307
               |.:.::.:                                     :.|:.||.:.|:
Mouse   320 APAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSR 384

  Fly   308 -----FIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMN 367
                 ...::.:||:.|:|.|:|.:....|:.:.|.::.:.:|...:.|.|.:..:||::|.::|
Mouse   385 SVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLN 449

  Fly   368 KRFRMYFQRIICC 380
            ...:...:.:|.|
Mouse   450 NGIKADLRALIHC 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	70/395 (18%)
		TM helix 1	85..111	CDD:320512	8/24 (33%)
		TM helix 2	118..144	CDD:320512	6/25 (24%)
		TM helix 3	156..186	CDD:320512	10/29 (34%)
		TM helix 4	197..218	CDD:320512	3/20 (15%)
		TM helix 5	251..280	CDD:320512	4/28 (14%)
		TM helix 6	299..329	CDD:320512	9/39 (23%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
Npy5r	NP_057917.2	7tmA_NPY5R	63..456	CDD:320520	70/395 (18%)
		TM helix 1	64..90	CDD:320520	8/24 (33%)
		TM helix 2	97..122	CDD:320520	6/24 (25%)
		TM helix 3	135..165	CDD:320520	10/29 (34%)
		TM helix 4	176..197	CDD:320520	3/20 (15%)
		TM helix 5	229..258	CDD:320520	4/28 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	323..346		1/22 (5%)
		TM helix 6	381..411	CDD:320520	6/29 (21%)
		TM helix 7	424..449	CDD:320520	6/24 (25%)