Protein Alignment TkR86C and Npy1r

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_035064.1
• Gene: Npy1r / 18166
• MGIID: 104963
• Length: 382
• Species: Mus musculus
• Alignment Length: 363
• Identity: 104/363 - (28%)
• Similarity: 178/363 - (49%)
• Gaps: 27/363 - (7%)

  Fly    71 SPTRPYE-----LPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADL 130
            ||...:|     ||.......|:.:|.::.:.::||..::.|:...:.||.|||..::|||.:||
Mouse    22 SPLLAFENDDCHLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDL 86

  Fly   131 LMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSR 195
            |::.:...|.|::.|...|.||...|.:|.||..|:::.|:|:||.|:.:|:..|::|...|.:.
Mouse    87 LVAVMCLPFTFVYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNN 151

  Fly   196 RKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYN-----GKSRTVCFMMWPDGRYPTSMADYAYN 255
            |...|.:.:||.|:...|.|.::|..:..:.:.|     .|.:.|||     .::|:.....:|.
Mouse   152 RHAYIGITVIWVLAVASSLPFVIYQILTDEPFQNVSLAAFKDKYVCF-----DKFPSDSHRLSYT 211

  Fly   256 LIILVLTYGIPMIVMLICY-SLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICW 319
            .::|||.|..|:..:.||| .:..|:...:..:.:..|.:..|.::|| :..|.::||..||:||
Mouse   212 TLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKIRDSKYRSSETKR-INIMLLSIVVAFAVCW 275

  Fly   320 LPYHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVG 384
            ||..:|......|:|:.:|.....::|..:..||.:..|||:.|.::||.|:...|.....|
Mouse   276 LPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFC--- 337

  Fly   385 LTRHRFDSPKSRLTNKNSSNRHTRGGYTVAHSLPNSSP 422
                .|.|..........|..||....|   ||..:||
Mouse   338 ----DFRSRDDDYETIAMSTMHTDVSKT---SLKQASP 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	87/295 (29%)
		TM helix 1	85..111	CDD:320512	5/25 (20%)
		TM helix 2	118..144	CDD:320512	10/25 (40%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	9/29 (31%)
		TM helix 6	299..329	CDD:320512	12/29 (41%)
		TM helix 7	342..367	CDD:320512	7/24 (29%)
Npy1r	NP_035064.1	7tmA_NPY1R	40..330	CDD:320517	87/295 (29%)
		TM helix 1	41..67	CDD:320517	5/25 (20%)
		TM helix 2	74..99	CDD:320517	10/24 (42%)
		TM helix 3	112..142	CDD:320517	11/29 (38%)
		TM helix 4	153..174	CDD:320517	6/20 (30%)
		TM helix 5	207..236	CDD:320517	9/28 (32%)
		TM helix 6	255..285	CDD:320517	12/30 (40%)
		TM helix 7	298..323	CDD:320517	7/24 (29%)