Protein Alignment TkR86C and npr-28

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_509416.2
• Gene: npr-28 / 181089
• WormBaseID: WBGene00018886
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 497
• Identity: 96/497 - (19%)
• Similarity: 195/497 - (39%)
• Gaps: 99/497 - (19%)

  Fly    68 LFPSPTRPYELPWEQKTIWAIIFGLMMF--VAIAGNGIVLWIV----------TGHRS--MRTVT 118
            :.||...|.|:.:|      |:|.::::  :|:.|.|...|::          :.:||  .:||.
 Worm    23 IVPSLNDPMEIQFE------IMFVMVLYSCLAVTGVGGNCWVLIKVIKQLSGCSSNRSRPYKTVV 81

  Fly   119 N----YFLLNLSIADLL-MSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAIS 178
            .    .:|:.||:.||. :..:..:...:::  :.:|||...|.::.|...:..|.|...|.|:|
 Worm    82 QSSAYVYLIILSVVDLFSLIPVPMIVTDVYV--NHFPFGLWACKLSYFCEAINKSLSPMVLTALS 144

  Fly   179 FDRYIAIVHPLK--RRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWP 241
            .|||||:.||..  .||::..:. :|.:.:::|.:...|....:::........:....|.....
 Worm   145 VDRYIAVCHPTLYWLRTTKFSLG-VLAVCFSVSLIFIIPVTKKATMQVMKDNTDEEIIKCAFDHG 208

  Fly   242 DGRYPTSMADYAYNLIILVLTYGIPMIVMLICY-SLMGRVLWGSR--SIGENTDRQMESMKSKRK 303
            |.      |.|.::....::.|.:|:.::...| :::.::...:|  ::|:.|.      .|..:
 Worm   209 DS------ASYVFDTAQAIVCYLVPLFIICAVYLAILHKLFIHTRFSTVGKKTS------ISLGR 261

  Fly   304 VVRMFIAIVSIFAICWLPY-----HLFFIYAYHNNQVASTKYVQHMYLG-------------FYW 350
            ||:..:.:|:.:.|||.||     |.........|...::..:..:...             |:.
 Worm   262 VVKCSVMVVAFYFICWTPYWTMRIHYLVTRFIETNSDGNSTVIDEVVAAVAEEVQDGIETSYFFG 326

  Fly   351 LAMSNAMVN---PLIYY-----WMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHT 407
            |.....|.|   .|||.     :....|...|...:                    |:|..:.:.
 Worm   327 LISKKRMHNIEIALIYILHSLTYAQSAFNWLFYSFL--------------------NRNLRSNNG 371

  Fly   408 RGGYTVAHSLPNSSPPTTQTLLAVLAQTLTQPKPQTQLLLSHHSPHPTQPSAAETKSQ-WKRSTM 471
            ||..|  .|..|:|........:.:..:||......|.:.||     .:.:..:|:|. .|:|..
 Worm   372 RGNGT--RSAANTSVFDNGNATSTVNTSLTPIWKNIQQMGSH-----IKTAGLDTRSALMKKSPF 429

  Fly   472 ETQIQQAPVTSSCREQRSAQQQQPPGSGTNRAAVECIMERPA 513
            :.:.:....:::..:..||...:|....|..:::..|..||:
 Worm   430 KGKSKIQSRSAAYLDCSSAHMLRPSSENTLSSSLLDIPRRPS 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	66/339 (19%)
		TM helix 1	85..111	CDD:320512	6/37 (16%)
		TM helix 2	118..144	CDD:320512	5/30 (17%)
		TM helix 3	156..186	CDD:320512	12/29 (41%)
		TM helix 4	197..218	CDD:320512	3/20 (15%)
		TM helix 5	251..280	CDD:320512	4/29 (14%)
		TM helix 6	299..329	CDD:320512	10/34 (29%)
		TM helix 7	342..367	CDD:320512	7/45 (16%)
npr-28	NP_509416.2	7tm_classA_rhodopsin-like	41..363	CDD:410626	65/356 (18%)
		TM helix 1	41..72	CDD:410626	4/30 (13%)
		TM helix 2	85..110	CDD:410626	5/24 (21%)
		TM helix 3	122..152	CDD:410626	12/29 (41%)
		TM helix 4	164..183	CDD:410626	2/19 (11%)
		TM helix 5	212..237	CDD:410626	4/24 (17%)
		TM helix 6	257..287	CDD:410626	9/29 (31%)
		TM helix 7	338..363	CDD:410626	5/44 (11%)