Protein Alignment TkR86C and npr-16

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001355490.1
• Gene: npr-16 / 180643
• WormBaseID: WBGene00006864
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 449
• Identity: 94/449 - (20%)
• Similarity: 175/449 - (38%)
• Gaps: 100/449 - (22%)

  Fly    93 MMFVAIAG-NGIVLWIVTGHRSMRTVTNYFLLNLSIADLL---------MSSLNCVFNFIFMLNS 147
            ::.||:.. |.|::.::.....:|::||.:::.|.:||.:         .:|||         ..
 Worm    27 LLLVALGSVNLIIILLIITRPYLRSITNVYMIGLCLADFIYLADLILVAATSLN---------GK 82

  Fly   148 DWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHP---LKRRTSRRKVRIILVLIWALS 209
            .||||...|.:.:.........||..:|.::.|||||:...   .:.||.|..: .:..|.|..:
 Worm    83 SWPFGPTICHLFHGTEATGKYASVLFVVLLAADRYIAMCKSDLCGRYRTYRTAI-FLSGLAWIAA 146

  Fly   210 CVLSAPCLLYS--------------SIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILV 260
            .:.|.|..:|:              ||...|       |:|...||...:    |.: |..:..|
 Worm   147 FICSLPLYVYADEIKVRMRPKNGTDSIENNH-------TLCIAHWPSPPH----AQW-YISVCSV 199

  Fly   261 LTYGIPMIVMLICY----SLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLP 321
            :.:.:|.:|:..||    ..:.....|||.:    .|...|..|.::|.|....:|....:||.|
 Worm   200 MIFILPGLVIFYCYYHVFCKLREAAKGSRRL----HRNKRSRSSYQRVTRSVQRVVLFHLLCWSP 260

  Fly   322 YHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLT 386
            :.||.:::.......:|:.::.:....:.....|..:||::|.:..:.||..|:.::
 Worm   261 FWLFNLFSAIFRVRITTQLMRIIVNIIHLFPYVNCALNPVLYAYRAENFRTAFKSLL-------- 317

  Fly   387 RHRFDSPKSRLTNKNSSNRHTRGGYTVAHSLPNSSPPTTQTLLAVLAQTLTQPKPQTQLLLSHHS 451
               |.|.:|                 |:..| |...|..:.:.:..|.|..:.......|
 Worm   318 ---FWSRRS-----------------VSSKL-NRPLPLPEDVRSTSASTYYRNSSNLDCL----- 356

  Fly   452 PHPTQPSAAETKSQWKRSTMETQIQQAPVTSSCR---EQRSAQ-QQQPPGSGTNRAAVE 506
                 .|:...||..:.:::....:::||.|:..   |::.|: |...|..|||...:|
 Worm   357 -----KSSLPIKSTMEPASVYQPEEESPVDSTENLEMERKKAELQAWRPYDGTNCEVLE 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	69/311 (22%)
		TM helix 1	85..111	CDD:320512	4/18 (22%)
		TM helix 2	118..144	CDD:320512	8/34 (24%)
		TM helix 3	156..186	CDD:320512	9/29 (31%)
		TM helix 4	197..218	CDD:320512	4/20 (20%)
		TM helix 5	251..280	CDD:320512	6/32 (19%)
		TM helix 6	299..329	CDD:320512	9/29 (31%)
		TM helix 7	342..367	CDD:320512	4/24 (17%)
npr-16	NP_001355490.1	7tm_classA_rhodopsin-like	45..305	CDD:410626	63/285 (22%)
		TM helix 2	53..79	CDD:410626	5/25 (20%)
		TM helix 3	91..121	CDD:410626	9/29 (31%)
		TM helix 4	134..153	CDD:410626	3/19 (16%)
		TM helix 5	190..215	CDD:410626	7/25 (28%)
		TM helix 6	238..268	CDD:410626	9/29 (31%)
		TM helix 7	281..305	CDD:410626	4/23 (17%)