Protein Alignment TkR86C and tkr-3

DIOPT Version :9

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001343603.1
• Gene: tkr-3 / 177285
• WormBaseID: WBGene00006428
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 389
• Identity: 101/389 - (25%)
• Similarity: 181/389 - (46%)
• Gaps: 47/389 - (12%)

  Fly    40 VVSLLSSIIDNRDNLESINEAK-----DFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIA 99
            :.|.::::|.....|....||:     ||            |||...:..||.:::.::.|:|:.
 Worm    10 LASTITTVIGGAGVLAEAGEAELSGDDDF------------YELTPVELIIWCMLYAIIAFMAVV 62

  Fly   100 GNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVAN 164
            ||.:||:|......:|::|.||:|||..|||........|.|...|..:|......|.|..:|..
 Worm    63 GNLLVLYITLFRLRVRSITTYFILNLGFADLFTGIFAIPFKFQAALFQEWFLPRSLCRIVPYVET 127

  Fly   165 VTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYN 229
            |.::.||||||..:...:..:......:.|.|..:..::|||.::.::|.|..|:.:.......|
 Worm   128 VALTVSVFTLVTSAVHEFRTMFFSKCSQMSPRSAKRCVLLIWIMAVLVSLPHGLFHNTYEFPDDN 192

  Fly   230 GKSRTVCFMMWPD-GRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWG-SRSIGENTD 292
            ..|...|..::|| |.:.|      ||:.::::.|.:|||::...|:::...:|. |:|..|..:
 Worm   193 NTSIVQCLPVYPDAGWWKT------YNVYLVIIQYFVPMIILDTAYTMIAVKIWSLSQSRVELDE 251

  Fly   293 RQMESMK-----------SKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYL 346
            .:|.:.|           ...:::|..|.:|:.|::||.|...:.:......::...||:..::.
 Worm   252 TKMATQKISVVSMVSPNTQLSQLMRTLIIVVACFSLCWFPLETYLLLNELKPEINGWKYINLVFF 316

  Fly   347 GFYWLAMSNAMVNPLIY------YWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSN 404
            ..:||||||:.:||:||      |  |:.:|..|::|   .|:...:...|.........||||
 Worm   317 FSHWLAMSNSCLNPIIYGLYNTKY--NEEYRRLFRQI---GCIWQRQKSLDDSMKPERRWNSSN 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	82/302 (27%)
		7tm_1	100..363	CDD:278431	74/275 (27%)
tkr-3	NP_001343603.1	7tm_GPCRs	47..344	CDD:391938	82/304 (27%)
		TM helix 1	48..74	CDD:341315	9/25 (36%)
		TM helix 2	81..106	CDD:341315	11/24 (46%)
		TM helix 3	119..149	CDD:341315	10/29 (34%)
		TM helix 4	160..181	CDD:341315	5/20 (25%)
		TM helix 5	209..238	CDD:341315	8/34 (24%)
		TM helix 6	254..299	CDD:341315	9/44 (20%)
		TM helix 7	312..337	CDD:341315	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X257
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910