DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TkR86C and ador-1

DIOPT Version :9

Sequence 1:	NP_001097741.1	Gene:	TkR86C / 41286	FlyBaseID:	FBgn0004841	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001040809.1	Gene:	ador-1 / 174890	WormBaseID:	WBGene00011878	Length:	362	Species:	Caenorhabditis elegans

Alignment Length:	311	Identity:	73/311 - (23%)
Similarity:	139/311 - (44%)	Gaps:	44/311 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 IWAIIFGLMMFVAIA-GNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSD 148
            :|..|..|::.:.|: .|.:|||:....:.:|||||.::.:|::.|.|..:|......:.::...
Worm     5 LWYAIAELLLSIHISFSNLLVLWVYVRSKHVRTVTNTYIFSLALTDFLAGALGIPLTVVSVMTRK 69

  Fly   149 WPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRI-ILVLIWALSCVL 212
             |.....|...:.:..:..:.|.|.::||:.|:|:.|....:..:||||..| :|...|.|..::
Worm    70 -PRTFYGCLFVHLILCILCTISTFHMLAIAIDKYVTICCRDRIFSSRRKRAIFLLTTSWILGLLV 133

  Fly   213 SAPCLL----YSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNL-IILVLTYGIPMIVMLI 272
            :...|.    ::...:....||:   :|..        |.:.||.|.: :|...|...|..::::
Worm   134 AILPLFNVFGFAETQSLFIENGE---MCHF--------TMVVDYRYLVYVIFFSTILAPTAIIVL 187

  Fly   273 CY-SLMGRVLWGSRSIG---ENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYH-- 331
            .| |:..|:....:.:.   ..::|: ..|..:||::|:.:.:|..:.|||.|.::.....|.
Worm   188 LYSSIYSRIRTEEKQVKCLLRQSERE-RRMAGRRKLIRILLILVVSYGICWYPLYIINTIDYFWP 251

  Fly   332 ----NNQVASTKYVQHMYLGFYWLAMSNAMVNPLIY-YWM---NKRFRMYF 374
                |:....|..:.||          :..:||||| |.|   .|..|.:|
Worm   252 EFSINSLTLWTVIMSHM----------SCALNPLIYAYGMPGFKKALRAFF 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	71/304 (23%)
TkR86C	NP_001097741.1	7tm_1	100..363	CDD:278431	62/278 (22%)
ador-1	NP_001040809.1	7tm_GPCRs	5..288	CDD:391938	71/305 (23%)
		TM helix 1	6..32	CDD:341315	8/25 (32%)
		TM helix 2	39..66	CDD:341315	6/26 (23%)
		TM helix 3	76..106	CDD:341315	7/29 (24%)
		TM helix 4	119..137	CDD:341315	4/17 (24%)
		TM helix 5	166..196	CDD:341315	7/29 (24%)
		TM helix 6	217..247	CDD:341315	8/29 (28%)
		TM helix 7	256..281	CDD:341315	10/34 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910