Protein Alignment TkR86C and Grpr

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_032203.1
• Gene: Grpr / 14829
• MGIID: 95836
• Length: 384
• Species: Mus musculus
• Alignment Length: 353
• Identity: 101/353 - (28%)
• Similarity: 173/353 - (49%)
• Gaps: 37/353 - (10%)

  Fly    89 IFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGS 153
            ::||::.:.:.||..::.|....:|||.|.|.|:.:|::.|||:.......:....|...|.||.
Mouse    47 VYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGR 111

  Fly   154 IYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIIL--VLIWALSCVLSAPC 216
            |.|.:..|:...:|..|||||.|:|.|||.|||.|:..:.|...::|.|  .|||.:|.:|:.|.
Mouse   112 IGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPE 176

  Fly   217 LLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVL 281
            .::|.:   |.::.|.....|:......:...:....:::...::.|.||:.::.:.|..:.|.|
Mouse   177 AVFSDL---HPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLAIISVYYYFIARNL 238

  Fly   282 WGSR-------SIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIY-AYHNNQVAST 338
            ..|.       :|  :..:|:||.|...|.|.:|   |.:||.||||.|:.::| :||.::|.::
Mouse   239 IQSAYNLPVEGNI--HVKKQIESRKRLAKTVLVF---VGLFAFCWLPNHVIYLYRSYHYSEVDTS 298

  Fly   339 KYVQHMYLGF--YWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKN 401
              :.|.....  ..||.:|:.|||...|.::|.||..|...:.||..||           :...:
Mouse   299 --MLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGL-----------MNRSH 350

  Fly   402 SSNRHTRGGYTVAHSLPNSSPPTTQTLL 429
            |:.|.|    |...|..:::|..|.:|:
Mouse   351 STGRST----TCMTSFKSTNPSATFSLI 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	88/296 (30%)
		TM helix 1	85..111	CDD:320512	5/21 (24%)
		TM helix 2	118..144	CDD:320512	6/25 (24%)
		TM helix 3	156..186	CDD:320512	14/29 (48%)
		TM helix 4	197..218	CDD:320512	8/22 (36%)
		TM helix 5	251..280	CDD:320512	4/28 (14%)
		TM helix 6	299..329	CDD:320512	13/30 (43%)
		TM helix 7	342..367	CDD:320512	8/26 (31%)
Grpr	NP_032203.1	7tmA_GRPR	42..334	CDD:320252	88/296 (30%)
		TM helix 1	43..69	CDD:320252	5/21 (24%)
		TM helix 2	76..102	CDD:320252	6/25 (24%)
		TM helix 3	114..144	CDD:320252	14/29 (48%)
		TM helix 4	156..176	CDD:320252	7/19 (37%)
		TM helix 5	208..233	CDD:320252	4/24 (17%)
		TM helix 6	258..288	CDD:320252	14/32 (44%)
		TM helix 7	302..327	CDD:320252	7/24 (29%)