Protein Alignment TkR86C and LOC1274295

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_061501239.1
• Gene: LOC1274295 / 1274295
• VectorBaseID: AGAMI1_004613
• Length: 428
• Species: Anopheles gambiae
• Alignment Length: 464
• Identity: 81/464 - (17%)
• Similarity: 145/464 - (31%)
• Gaps: 161/464 - (34%)

  Fly    20 ENSPVLTYMETEDDPNFRNSKLAAAPHTVHMMDSGFL-------AINRQC----------LVKGK 67
            ::||:...|: ::..:.:...:...||: .:::.|.:       ||:.||          |:|.|
Mosquito    37 DSSPLQPAMD-KNKESLKVKLMVRRPHS-QLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAK 99

  Fly    68 AILAREPKSSNE--HMIDDLPKHAHDQHTLSILRDFIDQLKLHNVYEINFYDPLDSS-----GKL 125
             |..|..:...|  |::::  ...|...:|:..:..:.:.:|        .|.|:|.     |.|
Mosquito   100 -IQQRPNREDLERLHILEE--DECHIDPSLAEKQRMLKKARL--------ADQLNSQIQHRPGPL 153

  Fly   126 AVIPMLIALWKCMLASETDICDQEVLKSIMNSVIAKFELQIPCKNAVIDATLSG-----SREEVH 185
            .:|.      |.:|.:|..|      :.|:...:..|:           ||..|     .....:
Mosquito   154 ELIK------KNILHTEKPI------EKIVKEGLVSFK-----------ATSEGLLTRPQHPHSY 195

  Fly   186 IIAEDGSLENSNGTTEHFNKKHDLVFVKTDLHPEDF--------------------------TPQ 224
            :..:|.|| :|...|.....:.|...|.|...|.|.                          :||
Mosquito   196 VTFDDDSL-SSESDTRQTPPRLDEAMVATSSSPTDVLQAAAASAGIVTMALTMPTAGQLVVTSPQ 259

  Fly   225 MFPSQAKAKLLRDAFNNEEDEDTFPDILVPA----------YMTAHSKNRVRQEDYTCLEVEFDS 279
            :.|.|.:.|.                |:|||          .:...|..:|:||.....|....|
Mosquito   260 ILPQQQQPKA----------------IVVPAPVPPPPPPPPPLPMASIIKVKQETANLYEELCQS 308

  Fly   280 QVALEKLMNEHEQVEGFEVQQGGILVALKKDSFFDDELIEKIAIAIATESRQSVSSVSFDLLKLG 344
            ..........|                          |....::|.:|.:...:||::      .
Mosquito   309 VTGTTASPVNH--------------------------LYSPCSLASSTSTLSPLSSIA------S 341

  Fly   345 PGASLVTLANSRRFEPECRVVLQIEVKPVSPGETSSEGISDEHHYEEYDEDDIMEEEEAPSA--- 406
            |....:|.....        :..:.||..:||:..:...|......:.......|.:..|||
Mosquito   342 PPPPPMTTTRLH--------LAPVSVKSDAPGKDKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQ 398

  Fly   407 RQDDTYDED 415
            :||.|..|:
Mosquito   399 KQDQTQPEE 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	53/335 (16%)
		TM helix 1	85..111	CDD:320512	3/25 (12%)
		TM helix 2	118..144	CDD:320512	8/30 (27%)
		TM helix 3	156..186	CDD:320512	4/34 (12%)
		TM helix 4	197..218	CDD:320512	4/20 (20%)
		TM helix 5	251..280	CDD:320512	9/38 (24%)
		TM helix 6	299..329	CDD:320512	3/29 (10%)
		TM helix 7	342..367	CDD:320512	2/24 (8%)
LOC1274295	XP_061501239.1	None