DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment TkR86C and P2ry6

DIOPT Version :9

Sequence 1:NP_001097741.1 Gene:TkR86C / 41286 FlyBaseID:FBgn0004841 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_476465.1 Gene:P2ry6 / 117264 RGDID:620269 Length:328 Species:Rattus norvegicus


Alignment Length:330 Identity:75/330 - (22%)
Similarity:146/330 - (44%) Gaps:59/330 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 TECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIAD 129
            |.|::....:...||        .::.:::.|.:..|..|:..:...|...|.:..:.|||::||
  Rat    16 TTCVYREDFKRLLLP--------PVYSVVLVVGLPLNVCVIAQICASRRTLTRSAVYTLNLALAD 72

  Fly   130 LLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPL---KR 191
            ||.:....:..:.:.....||||.:.|.:..|:....:..|:..|..|||.||:.|.|||   .:
  Rat    73 LLYACSLPLLIYNYARGDHWPFGDLACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHK 137

  Fly   192 RTSRRKVRIILVLIWALSCVLSAPCL---LYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADY- 252
            |..||...::..::|   .|::|.||   ::::...:     ::||||:.:.|    |.....| 
  Rat   138 RGGRRAAWVVCGVVW---LVVTAQCLPTAVFAATGIQ-----RNRTVCYDLSP----PILSTRYL 190

  Fly   253 AYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAI 317
            .|.:.:.|:.:.:|...:|.||..|.|     |...::......:.:.:.|..||.:.:.::|.|
  Rat   191 PYGMALTVIGFLLPFTALLACYCRMAR-----RLCRQDGPAGPVAQERRSKAARMAVVVAAVFVI 250

  Fly   318 CWLPYHLFFIYAYHNNQVASTKYV----------------QHMYLGFYWLAMSNAMVNPLIYYWM 366
            .:||:|           :..|.|:                ...|.|....|.:|::::|:::|:.
  Rat   251 SFLPFH-----------ITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASANSVLDPILFYFT 304

  Fly   367 NKRFR 371
            .::||
  Rat   305 QQKFR 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TkR86CNP_001097741.1 7tm_4 92..376 CDD:304433 71/303 (23%)
7tm_1 100..363 CDD:278431 67/285 (24%)
P2ry6NP_476465.1 7tm_GPCRs 27..312 CDD:421689 73/319 (23%)
TM helix 1 27..54 CDD:410628 5/34 (15%)
TM helix 2 61..86 CDD:410628 7/24 (29%)
TM helix 3 99..129 CDD:410628 9/29 (31%)
TM helix 4 142..164 CDD:410628 6/24 (25%)
TM helix 5 189..218 CDD:410628 9/33 (27%)
TM helix 6 232..262 CDD:410628 9/40 (23%)
TM helix 7 280..305 CDD:410628 6/24 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.