Protein Alignment TkR86C and tacr3

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_002934808.1
• Gene: tacr3 / 100486525
• XenbaseID: XB-GENE-985728
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 305
• Identity: 125/305 - (40%)
• Similarity: 196/305 - (64%)
• Gaps: 15/305 - (4%)

  Fly    79 PWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIF 143
            || :..:|::.:|.|:.||:.||.||:||:..|:.|||||||||:||:.:|..|::.|.:.|||:
 Frog    46 PW-RIALWSLAYGSMVAVAVFGNIIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIY 109

  Fly   144 MLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWAL 208
            .|:::|.||..||..:||....::..|::::.||:.|||:||:.|||.|.|....::::..||..
 Frog   110 ALHNEWYFGEAYCRFHNFFPITSIFASIYSMSAIAVDRYMAIIDPLKPRLSATSTKVVIGSIWIF 174

  Fly   209 SCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWP--DGRYPTSMADYAYNLIILVLTYGIPMIVML 271
            :.:|:.|..|||.|...     ::||:|.::||  |.|       ..|..|:::|.|.:|:|||.
 Frog   175 AILLAFPQCLYSKIRVT-----RTRTLCMLVWPGKDER-------LTYQFILVLLVYVLPLIVMG 227

  Fly   272 ICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVA 336
            :.|:::|..|||....|:.:|:..|.:::|||||:|.|.:|..|||||||||:||:....:.::.
 Frog   228 VTYTIVGITLWGGEIPGDTSDKYHEQLRAKRKVVKMMIVVVVTFAICWLPYHIFFLADALDIKLD 292

  Fly   337 STKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCC 381
            ..||:|.:||..:|||||:.|.||:||..:|||||..|:|....|
 Frog   293 RWKYIQQIYLAIFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWC 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	120/291 (41%)
		TM helix 1	85..111	CDD:320512	11/25 (44%)
		TM helix 2	118..144	CDD:320512	13/25 (52%)
		TM helix 3	156..186	CDD:320512	10/29 (34%)
		TM helix 4	197..218	CDD:320512	4/20 (20%)
		TM helix 5	251..280	CDD:320512	10/28 (36%)
		TM helix 6	299..329	CDD:320512	19/29 (66%)
		TM helix 7	342..367	CDD:320512	13/24 (54%)
tacr3	XP_002934808.1	7tm_GPCRs	50..330	CDD:475119	120/291 (41%)
		TM helix 1	52..76	CDD:320669	11/23 (48%)
		TM helix 2	85..107	CDD:320669	9/21 (43%)
		TM helix 3	123..145	CDD:320669	5/21 (24%)
		TM helix 4	166..182	CDD:320669	3/15 (20%)
		TM helix 5	208..231	CDD:320669	8/22 (36%)
		TM helix 6	261..283	CDD:320669	14/21 (67%)
		TM helix 7	298..323	CDD:320669	13/24 (54%)