DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TkR86C and tacr3

DIOPT Version :9

Sequence 1:	NP_001097741.1	Gene:	TkR86C / 41286	FlyBaseID:	FBgn0004841	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_002934808.1	Gene:	tacr3 / 100486525	XenbaseID:	XB-GENE-985728	Length:	431	Species:	Xenopus tropicalis

Alignment Length:	305	Identity:	125/305 - (40%)
Similarity:	196/305 - (64%)	Gaps:	15/305 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 PWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIF 143
            || :..:|::.:|.|:.||:.||.||:||:..|:.|||||||||:||:.:|..|::.|.:.|||:
Frog    46 PW-RIALWSLAYGSMVAVAVFGNIIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIY 109

  Fly   144 MLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWAL 208
            .|:::|.||..||..:||....::..|::::.||:.|||:||:.|||.|.|....::::..||..
Frog   110 ALHNEWYFGEAYCRFHNFFPITSIFASIYSMSAIAVDRYMAIIDPLKPRLSATSTKVVIGSIWIF 174

  Fly   209 SCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWP--DGRYPTSMADYAYNLIILVLTYGIPMIVML 271
            :.:|:.|..|||.|...     ::||:|.::||  |.|       ..|..|:::|.|.:|:|||.
Frog   175 AILLAFPQCLYSKIRVT-----RTRTLCMLVWPGKDER-------LTYQFILVLLVYVLPLIVMG 227

  Fly   272 ICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVA 336
            :.|:::|..|||....|:.:|:..|.:::|||||:|.|.:|..|||||||||:||:....:.::.
Frog   228 VTYTIVGITLWGGEIPGDTSDKYHEQLRAKRKVVKMMIVVVVTFAICWLPYHIFFLADALDIKLD 292

  Fly   337 STKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCC 381
            ..||:|.:||..:|||||:.|.||:||..:|||||..|:|....|
Frog   293 RWKYIQQIYLAIFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWC 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tm_4	92..376	CDD:304433	119/285 (42%)
TkR86C	NP_001097741.1	7tm_1	100..363	CDD:278431	108/264 (41%)
tacr3	XP_002934808.1	7tm_4	58..>181	CDD:304433	51/122 (42%)
tacr3	XP_002934808.1	7tm_1	66..319	CDD:278431	108/264 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	246	1.000	Domainoid score	I2128
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314830at33208
OrthoFinder	1	1.000	-	-		FOG0000620
OrthoInspector	1	1.000	-	-		mtm9492
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X257
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920