Protein Alignment TkR86C and grpr

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_002938295.1
• Gene: grpr / 100486428
• XenbaseID: XB-GENE-1013137
• Length: 384
• Species: Xenopus tropicalis
• Alignment Length: 396
• Identity: 111/396 - (28%)
• Similarity: 187/396 - (47%)
• Gaps: 53/396 - (13%)

  Fly    42 SLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAI--IFGLMMFVAIAGNGIV 104
            :|.||.::     :|.|.:.|   :..:|..|            :||  ::|:::.:.:.||..:
 Frog    16 ALTSSCLN-----QSSNHSSD---DWFYPGVT------------YAIVPVYGIIILIGLIGNITL 60

  Fly   105 LWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVST 169
            :.|....:|||.|.|.|:.:|::.|||:.......:....|...|.||.:.|.:..|:...:|..
 Frog    61 IKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASRFLADKWLFGRVGCKLIPFIQLTSVGV 125

  Fly   170 SVFTLVAISFDRYIAIVHP--LKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKS 232
            |||||.|::.|||.|||.|  ::...:..|:.|...|||.||..|:.|..::|.:   |.:..|.
 Frog   126 SVFTLTALAADRYTAIVRPMDIQANNALTKICIKAALIWILSMTLAIPEAVFSDM---HPFYDKE 187

  Fly   233 RTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRS---IGENTD-- 292
            ..|.|:......:...:....::....::.|.||:.::.:.|..:.:.|..|.|   :..|..
 Frog   188 INVTFVSCAPYPHSNGLHPRIHSTTSFLIFYVIPLSIISVYYYFIAKNLMRSASNMPVEGNVHVR 252

  Fly   293 RQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIY-AYHNNQVASTKYVQHMYLGFYW---LAM 353
            ||:||.|...|.|.:|   |.:||.||||.|:.::| :||.::|.::  |.| |:....   ||.
 Frog   253 RQIESRKRLAKTVLVF---VGLFAFCWLPIHIIYLYRSYHYSEVDTS--VLH-YISSICARVLAF 311

  Fly   354 SNAMVNPLIYYWMNKRFRMYFQRIICCC---------CVGLTRHRFDSPKSRLTNKNSSNRHTRG 409
            :|:.|||...|.::|.||..|...:.||         .:|.:..|..|.||  ||.:.::.....
 Frog   312 TNSCVNPFALYLLSKSFRKQFNNQLFCCRPRLIVRTQSMGRSTTRMTSLKS--TNHSMASFSLIN 374

  Fly   410 GYTVAH 415
            |..:.|
 Frog   375 GKHICH 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	91/302 (30%)
		TM helix 1	85..111	CDD:320512	6/27 (22%)
		TM helix 2	118..144	CDD:320512	6/25 (24%)
		TM helix 3	156..186	CDD:320512	13/29 (45%)
		TM helix 4	197..218	CDD:320512	9/20 (45%)
		TM helix 5	251..280	CDD:320512	4/28 (14%)
		TM helix 6	299..329	CDD:320512	13/30 (43%)
		TM helix 7	342..367	CDD:320512	9/27 (33%)
grpr	XP_002938295.1	7tmA_GRPR	40..332	CDD:320252	91/300 (30%)
		TM helix 1	41..67	CDD:320252	6/25 (24%)
		TM helix 2	74..100	CDD:320252	6/25 (24%)
		TM helix 3	112..142	CDD:320252	13/29 (45%)
		TM helix 4	154..174	CDD:320252	8/19 (42%)
		TM helix 5	206..231	CDD:320252	4/24 (17%)
		TM helix 6	256..286	CDD:320252	14/32 (44%)
		TM helix 7	300..325	CDD:320252	8/24 (33%)