Protein Alignment TkR86C and kissr1b

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001165295.1
• Gene: kissr1b / 100329184
• XenbaseID: XB-GENE-29077371
• Length: 367
• Species: Xenopus tropicalis
• Alignment Length: 354
• Identity: 103/354 - (29%)
• Similarity: 172/354 - (48%)
• Gaps: 46/354 - (12%)

  Fly    52 DNLESINEAKDF--LTECLFPSP-------------TRPYEL-PWEQKTIWAIIFGLMMFVAIAG 100
            |||...:.:.|.  :|....|||             |.|..: .|    :..:.|.|:|.|.:.|
 Frog     2 DNLSLFSCSNDSTGITRLYQPSPAAGCNSSVYGSDQTPPLLVDAW----LVPLFFALIMLVGLVG 62

  Fly   101 NGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNF---IFMLNSDWPFGSIYCTINNFV 162
            |.:|:::::.||.||||||:::.||:..|:  :.|.|...|   ::.|.| |.||...|...|::
 Frog    63 NSLVIYVISKHRQMRTVTNFYIANLATTDI--TFLVCCVPFTATLYPLPS-WVFGDFMCRCVNYL 124

  Fly   163 ANVTVSTSVFTLVAISFDRYIAIVHP---LKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMT 224
            ..||...:..||.|:|.||....|:|   |:.||.|..:.:.|. ||..|.|||.|..:|..:.|
 Frog   125 QQVTAQATCITLTAMSVDRCYVTVYPLQSLRHRTPRMAMAVSLG-IWIGSFVLSIPFAMYQKLST 188

  Fly   225 KHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSL----MGRVLWGSR 285
            .::|.  .:|.|.     ..:||.:...|:.|...:..|.:|::.:.|||:.    |||.:  ..
 Frog   189 GYWYG--PQTYCI-----EAFPTVLHQKAFILYTFLAVYLLPLLTICICYAFMLKRMGRPV--VE 244

  Fly   286 SIGENTDRQMESMKS---KRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLG 347
            .|..|...|:.:.:|   :.|:.||.:.||.:|.|||.|..||.::...::....:.....:.:.
 Frog   245 PIDNNYQVQLLAERSEAMRTKISRMVVVIVLLFTICWGPVQLFILFQAFDSSFEKSYETYKLKIF 309

  Fly   348 FYWLAMSNAMVNPLIYYWMNKRFRMYFQR 376
            .:.::.||:.:||::|.:|...||..|::
 Frog   310 AHCMSYSNSSINPIVYAFMGANFRKSFKK 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	91/302 (30%)
		TM helix 1	85..111	CDD:320512	7/25 (28%)
		TM helix 2	118..144	CDD:320512	8/28 (29%)
		TM helix 3	156..186	CDD:320512	10/29 (34%)
		TM helix 4	197..218	CDD:320512	8/20 (40%)
		TM helix 5	251..280	CDD:320512	9/32 (28%)
		TM helix 6	299..329	CDD:320512	13/32 (41%)
		TM helix 7	342..367	CDD:320512	5/24 (21%)
kissr1b	NP_001165295.1	7tmA_KiSS1R	46..336	CDD:320223	92/306 (30%)
		TM helix 1	47..73	CDD:320223	7/25 (28%)
		TM helix 2	80..106	CDD:320223	8/27 (30%)
		TM helix 3	118..148	CDD:320223	10/29 (34%)
		TM helix 4	160..180	CDD:320223	8/20 (40%)
		TM helix 5	208..237	CDD:320223	7/28 (25%)
		TM helix 6	261..291	CDD:320223	12/29 (41%)
		TM helix 7	304..329	CDD:320223	5/24 (21%)