Protein Alignment TkR86C and tacr1

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001106489.1
• Gene: tacr1 / 100127678
• XenbaseID: XB-GENE-5835469
• Length: 407
• Species: Xenopus tropicalis
• Alignment Length: 311
• Identity: 119/311 - (38%)
• Similarity: 189/311 - (60%)
• Gaps: 16/311 - (5%)

  Fly    75 PYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVF 139
            |:..|..|..:|:|.:.:::.|::.||.||:||:..|:.|||||||||:||:.|:..||:.|.|.
 Frog    24 PFLQPAWQIALWSIAYSIIVIVSVVGNIIVMWIILAHKRMRTVTNYFLVNLAFAEASMSAFNTVI 88

  Fly   140 NFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVL 204
            ||.:.:::.|.:|.|||..:||.....|.:|::::.||:.|||:||:||||.|.|....||::.:
 Frog    89 NFTYAIHNHWYYGLIYCKFHNFFPISAVFSSIYSMTAIALDRYMAIIHPLKPRLSATATRIVIAV 153

  Fly   205 IWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIV 269
            ||..:..|:.|...::::...     ..|.||:|.||:..  ....:..|.:::..|.|.:|::|
 Frog   154 IWGFAFALAFPQGYFATVEPT-----PDRVVCYMEWPESE--NRKFEKVYQVLLFGLIYFLPLLV 211

  Fly   270 MLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQ 334
            :...|:.:|..||.|...|:::||..|.:.:|||||:|.|.:|..|||||||||::|:.     |
 Frog   212 IGCSYTFIGMTLWASEIPGDSSDRYHEQVVAKRKVVKMMIVVVCTFAICWLPYHIYFLL-----Q 271

  Fly   335 V----ASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCC 381
            :    .|.|:.|.:|||..||.||:.|.||:||..:|.|||:.|:.:...|
 Frog   272 LFLPDESQKFYQQLYLGIMWLGMSSTMYNPIIYCCLNDRFRIGFKHVFRWC 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	114/293 (39%)
		TM helix 1	85..111	CDD:320512	9/25 (36%)
		TM helix 2	118..144	CDD:320512	14/25 (56%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	7/28 (25%)
		TM helix 6	299..329	CDD:320512	18/29 (62%)
		TM helix 7	342..367	CDD:320512	13/24 (54%)
tacr1	NP_001106489.1	7tmA_NK1R	33..315	CDD:320668	114/293 (39%)
		TM helix 1	34..60	CDD:320668	9/25 (36%)
		TM helix 2	67..93	CDD:320668	14/25 (56%)
		TM helix 3	105..135	CDD:320668	11/29 (38%)
		TM helix 4	146..167	CDD:320668	6/20 (30%)
		TM helix 5	193..222	CDD:320668	7/28 (25%)
		TM helix 6	241..271	CDD:320668	18/34 (53%)
		TM helix 7	283..308	CDD:320668	13/24 (54%)