Protein Alignment TkR86C and tacr1a

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001257407.1
• Gene: tacr1a / 100003539
• ZFINID: ZDB-GENE-060526-185
• Length: 426
• Species: Danio rerio
• Alignment Length: 494
• Identity: 153/494 - (30%)
• Similarity: 238/494 - (48%)
• Gaps: 109/494 - (22%)

  Fly    63 FLTECLFPS-------PTRPYELPWEQ-------KTIWAIIFGLMMFVAIAGNGIVLWIVTGHRS 113
            |:|...|||       .....|:.|.|       ..:||:.:..::.|::.||..|:||:..|:.
Zfish     4 FITSTDFPSNWTVNSTAQNETEIYWNQFVQPVWRIVLWAVAYSTIVVVSVVGNITVIWIILAHKR 68

  Fly   114 MRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAIS 178
            |||||||||:||:.|:..||:.|.|.||::.::::|.||..||..:||.....|..|::::.||:
Zfish    69 MRTVTNYFLVNLAFAEASMSAFNTVINFVYSVHNEWYFGLYYCRFHNFFPIAAVFASIYSMTAIA 133

  Fly   179 FDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNG----KSRTVCFMM 239
            .|||:||:|||::|.|..:.::::.:||.|:.:|:.|         ::||:.    ..|.||::.
Zfish   134 LDRYMAIIHPLQQRMSATQTKVVIGVIWILALLLAFP---------QYYYSDTDQLPGRVVCYID 189

  Fly   240 WPDGRYPTSMADY--AYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKR 302
            ||:    .::.|:  .|.:.:.||.|.:|::||...|.::|..||.|...|:::||..|.:.:||
Zfish   190 WPE----YTLLDFKTMYFVCVAVLIYFLPLLVMGCAYLVVGLTLWASEIPGDSSDRYQEQLTAKR 250

  Fly   303 KVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMN 367
            |||:|.|.:|..||:||||||::|:.......:....::|.:||...|||||:.|.||:||..:|
Zfish   251 KVVKMMIVVVCTFAVCWLPYHVYFLIHQFYPHLFEHTFIQQVYLTIMWLAMSSTMYNPIIYCCLN 315

  Fly   368 KRFRMYF-QRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRGGYTVAHSLPNSSPPTTQTLLAV 431
            .|||..| |...||.||                       ..|.|   ..|...|....||
Zfish   316 DRFRAGFKQAFRCCPCV-----------------------PEGSY---EGLELKSTRYLQT---- 350

  Fly   432 LAQTLTQPKPQTQLLLSHHSPHPTQPSAAETKSQWKRSTMETQIQQAPVTSSCREQRSAQQQQPP 496
                      ||.|                    ::.|.|||.:       ||..|.|....:..
Zfish   351 ----------QTSL--------------------YRASRMETSV-------SCVMQPSEDGHKVT 378

  Fly   497 GSGTNRAAVECIMERP-----ADGSSSPLCLSINNSIGE 530
            ......|||:.....|     ::||||   .||:.::.|
Zfish   379 FGSVRGAAVKPAARSPSREFTSNGSSS---RSISKTVSE 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	111/295 (38%)
		TM helix 1	85..111	CDD:320512	8/25 (32%)
		TM helix 2	118..144	CDD:320512	14/25 (56%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	5/20 (25%)
		TM helix 5	251..280	CDD:320512	10/30 (33%)
		TM helix 6	299..329	CDD:320512	17/29 (59%)
		TM helix 7	342..367	CDD:320512	13/24 (54%)
tacr1a	NP_001257407.1	7tmA_NK1R	39..322	CDD:320668	111/295 (38%)
		TM helix 1	40..66	CDD:320668	8/25 (32%)
		TM helix 2	73..99	CDD:320668	14/25 (56%)
		TM helix 3	111..141	CDD:320668	11/29 (38%)
		TM helix 4	152..173	CDD:320668	5/29 (17%)
		TM helix 5	199..228	CDD:320668	9/28 (32%)
		TM helix 6	247..277	CDD:320668	17/29 (59%)
		TM helix 7	290..315	CDD:320668	13/24 (54%)