Protein Alignment TkR86C and gpr83

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_021332117.1
• Gene: gpr83 / 100002786
• ZFINID: ZDB-GENE-060526-286
• Length: 351
• Species: Danio rerio
• Alignment Length: 303
• Identity: 95/303 - (31%)
• Similarity: 173/303 - (57%)
• Gaps: 17/303 - (5%)

  Fly    76 YELPWEQKTIWAII---FGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNC 137
            ||....:.||.|::   :.:::.:::.||.:|..:|..::.|.:||:.|::||:|||:|::.||.
Zfish    38 YESESHRPTIRALLIVAYSVIIIISLFGNVVVCHVVIKNKRMHSVTSLFIMNLAIADILITLLNT 102

  Fly   138 VFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIIL 202
            .|..:..:.|.|.||.:.|.::.|....:|..||.|||||:.||:..::||:|:|.||.:....:
Zfish   103 PFTLVRFVYSTWVFGKVMCHVSRFAQYCSVHVSVLTLVAIAIDRHQVVMHPMKQRMSRLQGIAWI 167

  Fly   203 VLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPM 267
            .:||.:....|.|..:|..::...:.|.:.|.||   ||...:|:.:.....:|...||.|.:|:
Zfish   168 GVIWVMGSCFSLPHAIYQKLLRFEFGNNRVRMVC---WPSFPHPSDLFWKYLDLASFVLLYVLPL 229

  Fly   268 IVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRK-VVRMFIAIVSIFAICWLPYHLFFIYAYH 331
            .::.|.|.::.:.:|...::|:.|..|..:.:.::| .::|.||:|::||:||.|.:.:.:
Zfish   230 AIISISYLVVAKKVWFQNAVGDVTLAQSAAQRRRKKTTLKMLIAVVAVFAVCWFPLNCYIV---- 290

  Fly   332 NNQVASTKYVQ---HMYLGFYWLAMSNAMVNPLIYYWMNKRFR 371
               :.|:|.:|   .:|..|:|||||:...||.||.|:|..||
Zfish   291 ---LLSSKVIQANNAVYFTFHWLAMSSTCYNPFIYCWLNHSFR 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	93/295 (32%)
		TM helix 1	85..111	CDD:320512	6/28 (21%)
		TM helix 2	118..144	CDD:320512	11/25 (44%)
		TM helix 3	156..186	CDD:320512	12/29 (41%)
		TM helix 4	197..218	CDD:320512	4/20 (20%)
		TM helix 5	251..280	CDD:320512	7/28 (25%)
		TM helix 6	299..329	CDD:320512	10/30 (33%)
		TM helix 7	342..367	CDD:320512	13/27 (48%)
gpr83	XP_021332117.1	7tmA_GPR83	49..333	CDD:320511	91/292 (31%)
		TM helix 1	50..76	CDD:320511	4/25 (16%)
		TM helix 2	83..108	CDD:320511	11/24 (46%)
		TM helix 3	121..151	CDD:320511	12/29 (41%)
		TM helix 4	162..183	CDD:320511	4/20 (20%)
		TM helix 5	213..242	CDD:320511	7/28 (25%)
		TM helix 6	262..292	CDD:320511	10/36 (28%)
		TM helix 7	301..326	CDD:320511	12/24 (50%)