Protein Alignment TkR86C and kiss1rb

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001104001.1
• Gene: kiss1rb / 100002715
• ZFINID: ZDB-GENE-060526-54
• Length: 364
• Species: Danio rerio
• Alignment Length: 365
• Identity: 99/365 - (27%)
• Similarity: 180/365 - (49%)
• Gaps: 45/365 - (12%)

  Fly    47 IIDNRD-NLESINEAKDFLTECL-FPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVT 109
            |:.|.| |:...|:     |:.: |.||     :|.....:..:.|.|:|||.:.||.||:::|.
Zfish    14 IMCNYDANIYQCNQ-----TDLMRFQSP-----VPLTDTWLVPLFFTLIMFVGLVGNLIVIYVVI 68

  Fly   110 GHRSMRTVTNYFLLNLSIADLLMSSLNCVFNF---IFMLNSDWPFGSIYCTINNFVANVTVSTSV 171
            .::.|:||||.:::||:..|:|.  |.|...|   :::|.| |.||...|.:.|::..||...:.
Zfish    69 KNQQMKTVTNLYIVNLATTDILF--LVCCVPFTATVYVLPS-WIFGDFMCRLVNYLQQVTAQATC 130

  Fly   172 FTLVAISFDRYIAIVHPLK---RRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSR 233
            .||.|:|.||:...|:||:   .||.:..:. :...||..|.:||.|..||....:.:::.  .:
Zfish   131 ITLSAMSVDRFYVTVYPLQSLHHRTPQMALS-VCTTIWICSSLLSVPIALYQHTESSYWFG--PQ 192

  Fly   234 TVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLM--------GRVLWGSRSIG-E 289
            |.|     ...:|:.:....|.|...:..|.:|:|.:.:||:.|        .:.:.|...|. :
Zfish   193 TYC-----TETFPSVIHKRVYLLYSFLAVYLLPLITICMCYTFMLKRMAQATVQPVQGCNQISLQ 252

  Fly   290 NTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYH-LFFIYAYHNNQVASTKYVQHMYLGFYWLAM 353
            .:..:.|:::|  :|.||.:.:|.:|.:||.|.. |..:.|:....|:.:..:..:.:..:.::.
Zfish   253 TSSERAEAVRS--RVSRMVVVMVLLFLLCWGPIQILILLQAFCAEDVSRSYTLYKLKIWAHGMSY 315

  Fly   354 SNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSP 393
            ||:.:||:||.:|...||..|:.:    |..:.:.|...|
Zfish   316 SNSSINPVIYAFMGANFRKAFRSV----CPLIFKRRSTEP 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	85/305 (28%)
		TM helix 1	85..111	CDD:320512	10/25 (40%)
		TM helix 2	118..144	CDD:320512	9/28 (32%)
		TM helix 3	156..186	CDD:320512	10/29 (34%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	8/36 (22%)
		TM helix 6	299..329	CDD:320512	10/30 (33%)
		TM helix 7	342..367	CDD:320512	6/24 (25%)
kiss1rb	NP_001104001.1	7tm_GPCRs	43..336	CDD:475119	85/305 (28%)
		TM helix 1	45..69	CDD:410628	10/23 (43%)
		TM helix 2	78..100	CDD:410628	8/23 (35%)
		TM helix 3	116..138	CDD:410628	6/21 (29%)
		TM helix 4	161..177	CDD:410628	5/16 (31%)
		TM helix 5	206..229	CDD:410628	6/22 (27%)
		TM helix 6	266..288	CDD:410628	8/21 (38%)
		TM helix 7	304..329	CDD:410628	6/24 (25%)