Protein Alignment TkR86C and si:dkey-202l22.3

DIOPT Version :10

• Sequence 1: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001108620.1
• Gene: si:dkey-202l22.3 / 100002553
• ZFINID: ZDB-GENE-131127-471
• Length: 377
• Species: Danio rerio
• Alignment Length: 465
• Identity: 115/465 - (24%)
• Similarity: 187/465 - (40%)
• Gaps: 109/465 - (23%)

  Fly    28 NTTLLGSLNRTEVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGL 92
            ||||..| |||:.:...|.                  |:.|.  ..:|..:|         ::.|
Zfish    13 NTTLSTS-NRTDPLDKFSG------------------TQLLL--RFKPLFIP---------LYAL 47

  Fly    93 MMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCV---FNFIFMLNSDWPFGSI 154
            ::.||..||..:|..:...:.:...||:|:.||:..|||| .|:||   .::.|.... |.||..
Zfish    48 VVVVAGVGNSFLLACILADKKLHNATNFFIGNLAAGDLLM-CLSCVPLTASYAFDAQG-WAFGRP 110

  Fly   155 YCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLY 219
            .|.:...|...||..||.:|.||:.|||:.:.:|::||.|......:.:.:||:|..|:||
Zfish   111 MCHLIPLVQGATVFASVLSLTAIAMDRYVVVAYPVRRRISVWGCGAVALGVWAVSLALAAP---- 171

  Fly   220 SSIMTKHY---YNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVL 281
            .|:.|::.   .:|....||...|........:    |:...|:.:|.||::.:.|.|..:...|
Zfish   172 PSLHTRYVDLRPSGMELVVCEEFWLGAERQRLL----YSCFFLLASYMIPLLSVSISYCAISVHL 232

  Fly   282 WGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNN--QVASTKYVQHM 344
            ......||.:..|....|.:||...:.:|.|..||:||||..:..:....::  |:....||..:
Zfish   233 RKHTLPGEPSQSQQRWSKQRRKTFSLLVASVLAFALCWLPLQVLNLLLDLDSDFQIVDKHYVNVL 297

  Fly   345 YLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRG 409
            .:..:.:|||:|..||.||..::.:.||:.:...|.|     ||...:..||..::|
Zfish   298 QVSCHLIAMSSACYNPFIYASLHSKVRMHLRGYFCPC-----RHSGQNLLSRCASRN-------- 349

  Fly   410 GYTVAHSLPNSSPPTTQTLLAVLAQTLTQPKPQTQLLLSHHSPHPTQPSAAETKSQWKRSTMETQ 474
                        |.|..||::.:.                                    ..|.|
Zfish   350 ------------PATCLTLISEVV------------------------------------VKENQ 366

  Fly   475 IQQAPVTSSC 484
            ..::||..||
Zfish   367 SPESPVPDSC 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	85/297 (29%)
		TM helix 1	85..111	CDD:320512	6/25 (24%)
		TM helix 2	118..144	CDD:320512	12/28 (43%)
		TM helix 3	156..186	CDD:320512	12/29 (41%)
		TM helix 4	197..218	CDD:320512	6/20 (30%)
		TM helix 5	251..280	CDD:320512	7/28 (25%)
		TM helix 6	299..329	CDD:320512	11/29 (38%)
		TM helix 7	342..367	CDD:320512	8/24 (33%)
si:dkey-202l22.3	NP_001108620.1	7tm_GPCRs	39..327	CDD:475119	87/306 (28%)
		TM helix 1	41..65	CDD:410628	7/32 (22%)
		TM helix 2	74..96	CDD:410628	11/22 (50%)
		TM helix 3	113..135	CDD:410628	8/21 (38%)
		TM helix 4	156..172	CDD:410628	6/19 (32%)
		TM helix 5	203..226	CDD:410628	6/26 (23%)
		TM helix 6	256..278	CDD:410628	8/21 (38%)
		TM helix 7	295..320	CDD:410628	8/24 (33%)