DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31278 and PDF

DIOPT Version :9

Sequence 1:	NP_731494.1	Gene:	CG31278 / 41282	FlyBaseID:	FBgn0051278	Length:	238	Species:	Drosophila melanogaster
Sequence 2:	NP_071736.1	Gene:	PDF / 64146	HGNCID:	30012	Length:	243	Species:	Homo sapiens

Alignment Length:	210	Identity:	89/210 - (42%)
Similarity:	126/210 - (60%)	Gaps:	9/210 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GTSPPANQSFRKWYQHLWTTERTNL----PPYNHFTQIGDPVLRQQAALVPKEHMASPEIKAIVE 81
            |...||.:  |.:::||   .|..|    ||::|..|:||||||..||.|.:..:..||::.:.:
Human    38 GVEGPALR--RSYWRHL---RRLVLGPPEPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQ 97

  Fly    82 RMVKVLRKFDCVGIAAPQIGVSLRIIAMEFKGRIRKELPEAVYQARQMSELPLTIFINPVLTVTN 146
            |:|:|:|:..|||::|||:||..:::|:|....:.:|.|......|||...||.:|:||.|.|.:
Human    98 RLVQVMRRRRCVGLSAPQLGVPRQVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLD 162

  Fly   147 YAKLKHPEGCMSVRGYSAEVERFEGVKLTGLDQLGNQSELALSGWNARIAQHEMDHLEGKLYTDH 211
            ...:..||||.||.|:.|.|.||:.|:::|||..|.|.....|||.|||.|||||||:|.|:.|.
Human   163 SRLVTFPEGCESVAGFLACVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDK 227

  Fly   212 MDRSTFACTCWEAVN 226
            ||..||....|..||
Human   228 MDSRTFTNVYWMKVN 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31278	NP_731494.1	Pep_deformylase	50..216	CDD:279645	74/165 (45%)
PDF	NP_071736.1	Pep_deformylase	67..224	CDD:238271	69/156 (44%)
PDF	NP_071736.1	Hydrophobic dimerization interface	165..175		4/9 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160277
Domainoid	1	1.000	149	1.000	Domainoid score	I4418
eggNOG	1	0.900	-	-		E1_COG0242
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69354
Inparanoid	1	1.050	166	1.000	Inparanoid score	I4173
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59626
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005148
OrthoInspector	1	1.000	-	-		otm40666
orthoMCL	1	0.900	-	-		OOG6_101584
Panther	1	1.100	-	-	LDO	PTHR10458
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17325
SonicParanoid	1	1.000	-	-		X4178
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.790