DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pug and EMB3127

DIOPT Version :9

Sequence 1:	NP_001014614.1	Gene:	pug / 41279	FlyBaseID:	FBgn0020385	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_191971.1	Gene:	EMB3127 / 825824	AraportID:	AT4G00620	Length:	360	Species:	Arabidopsis thaliana

Alignment Length:	291	Identity:	156/291 - (53%)
Similarity:	204/291 - (70%)	Gaps:	4/291 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 GAKIISGTAVAKSIREELRNEVTAMSKQLADFVPGLRIVQVGGREDSNVYIRMKIKAATEIGIDA 101
            ||.:|.|.||||.||:|:..||:.| |:....:|||.::.||.|:||..|:|.|.||...:||.:
plant    68 GAIVIDGKAVAKKIRDEITIEVSRM-KESIGVIPGLAVILVGDRKDSATYVRNKKKACDSVGIKS 131

  Fly   102 AHVQLPRSITEVELLDKINDLNEDPRVHGIIVQMPLDCDTPIDSHRITDAVSPEKDVDGLHTVNE 166
            ..|:|....:|.|:|..::..|:||.||||:||:||  .:.:|...|.:|||.||||||.|.:|.
plant   132 FEVRLAEDSSEEEVLKSVSGFNDDPSVHGILVQLPL--PSHMDEQNILNAVSIEKDVDGFHPLNI 194

  Fly   167 GRLAI-GDLGGFLPCTPWGCLELIRRSGVEIAGARAVVLGRSKIVGTPAAELLKWANATVTVCHS 230
            ||||: |....|:||||.||:||:.|..:||.|.||||:|||.|||.|||.||:..:|||::.||
plant   195 GRLAMRGREPLFVPCTPKGCIELLHRYNIEIKGKRAVVIGRSNIVGMPAALLLQREDATVSIIHS 259

  Fly   231 KTRNLEEITRSADILVVGIGVAEMVKGSWIKPGAVVIDCGINVKPDASKASGSKLVGDVDYAEAL 295
            :|:|.|||||.|||::..:|...||:|||||||||:||.|||...|.|.|.|.:||||:.|.||.
plant   260 RTKNPEEITREADIIISAVGQPNMVRGSWIKPGAVLIDVGINPVEDPSAARGYRLVGDICYEEAS 324

  Fly   296 QVAGHLTPVPGGVGPMTVAMLMKNTVRSAAR 326
            :||..:|||||||||||:|||:.||:.||.|
plant   325 KVASAITPVPGGVGPMTIAMLLSNTLTSAKR 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pug	NP_001014614.1	FolD	39..330	CDD:223268	154/289 (53%)
		THF_DHG_CYH	40..159	CDD:279147	52/118 (44%)
		NAD_bind_m-THF_DH_Cyclohyd	154..324	CDD:133448	102/170 (60%)
		FTHFS	350..968	CDD:279592
EMB3127	NP_191971.1	PLN02616	1..360	CDD:215332	156/291 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	196	1.000	Domainoid score	I900
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100216
Panther	1	1.100	-	-	O	PTHR48099
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910