DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pug and AT4G00600

DIOPT Version :9

Sequence 1:	NP_001014614.1	Gene:	pug / 41279	FlyBaseID:	FBgn0020385	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_191969.1	Gene:	AT4G00600 / 825813	AraportID:	AT4G00600	Length:	310	Species:	Arabidopsis thaliana

Alignment Length:	304	Identity:	139/304 - (45%)
Similarity:	184/304 - (60%)	Gaps:	43/304 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 WTAEPAIKMS---GAKIISGTAVAKSIREELRNEVTAMSKQLADFVPGLRIVQVGGREDSNVYIR 88
            |....:|:.|   .|.:|.|.|.||.||::::.||:.| |:....||.         |||
plant    41 WRCTLSIRSSSSPSAIVIDGKAEAKKIRDDIKIEVSRM-KESIGVVPA---------EDS----- 90

  Fly    89 MKIKAATEIGIDAAHVQLPRSITEVELLDKINDLNEDPRVHGIIVQMPLDCDTPIDSHRITDAVS 153
                                  :|.|:|..::..|:||.|||::||:||  .:.:|...|.:|||
plant    91 ----------------------SEEEVLKYVSGFNDDPSVHGVLVQLPL--PSHMDEQNILNAVS 131

  Fly   154 PEKDVDGLHTVNEGRLAI-GDLGGFLPCTPWGCLELIRRSGVEIAGARAVVLGRSKIVGTPAAEL 217
            .||||||.|.:|.||||: |....|:||||.||:||:.|..:|..|.||||:|||.|||.|||.|
plant   132 IEKDVDGFHPLNIGRLAMRGREPLFVPCTPKGCIELLHRYNIEFKGKRAVVIGRSNIVGMPAALL 196

  Fly   218 LKWANATVTVCHSKTRNLEEITRSADILVVGIGVAEMVKGSWIKPGAVVIDCGINVKPDASKASG 282
            |:..:|||::.||:|.|.||:||.||||:..:|...||:|||||||||:||.||....|.|.|.|
plant   197 LQKEDATVSIIHSRTMNPEELTRQADILISAVGKPNMVRGSWIKPGAVLIDVGIKPVEDPSAAGG 261

  Fly   283 SKLVGDVDYAEALQVAGHLTPVPGGVGPMTVAMLMKNTVRSAAR 326
            .:||||:.|.||.::|..:|||||.|||||:|||:.||:.||.|
plant   262 ERLVGDICYVEASKIASAITPVPGDVGPMTIAMLLSNTLTSAKR 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pug	NP_001014614.1	FolD	39..330	CDD:223268	135/289 (47%)
		THF_DHG_CYH	40..159	CDD:279147	37/118 (31%)
		NAD_bind_m-THF_DH_Cyclohyd	154..324	CDD:133448	98/170 (58%)
		FTHFS	350..968	CDD:279592
AT4G00600	NP_191969.1	PLN02616	1..310	CDD:215332	139/304 (46%)
		THF_DHG_CYH	57..137	CDD:279147	37/118 (31%)
		NAD_bind_m-THF_DH_Cyclohyd	132..304	CDD:133448	99/171 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	196	1.000	Domainoid score	I900
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100216
Panther	1	1.100	-	-	O	PTHR48099
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910