DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pug and AT3G12290

DIOPT Version :9

Sequence 1:	NP_001014614.1	Gene:	pug / 41279	FlyBaseID:	FBgn0020385	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_187837.1	Gene:	AT3G12290 / 820409	AraportID:	AT3G12290	Length:	299	Species:	Arabidopsis thaliana

Alignment Length:	290	Identity:	159/290 - (54%)
Similarity:	203/290 - (70%)	Gaps:	4/290 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 AKIISGTAVAKSIREELRNEVTAMSKQLADFVPGLRIVQVGGREDSNVYIRMKIKAATEIGIDAA 102
            ||||.|.|:|.:||.|:..||..:|::... ||||.:|.||.|:||..|:..|.||..|:||.:.
plant     9 AKIIDGKAIAHTIRSEIAEEVRGLSEKHGK-VPGLAVVIVGSRKDSQTYVNTKRKACAEVGIKSF 72

  Fly   103 HVQLPRSITEVELLDKINDLNEDPRVHGIIVQMPLDCDTPIDSHRITDAVSPEKDVDGLHTVNEG 167
            .|.||..::|.:|:.|:::||.:|.||||:||:||  ...|:...|..|:|.:|||||.|.:|.|
plant    73 DVGLPEEVSEADLISKVHELNSNPDVHGILVQLPL--PKHINEEHILGAISIDKDVDGFHPLNIG 135

  Fly   168 RLAI-GDLGGFLPCTPWGCLELIRRSGVEIAGARAVVLGRSKIVGTPAAELLKWANATVTVCHSK 231
            :||: |....||||||.|||||:.||||:|.|.||||:|||.|||.|.:.||..|:||||..||.
plant   136 KLAMKGREPLFLPCTPKGCLELLARSGVKIKGQRAVVVGRSNIVGLPVSLLLLKADATVTTVHSH 200

  Fly   232 TRNLEEITRSADILVVGIGVAEMVKGSWIKPGAVVIDCGINVKPDASKASGSKLVGDVDYAEALQ 296
            |::.|.|.|.|||::...|.|.|:||:||||||.|||.|.|...|.||.||.:||||||:|||.:
plant   201 TKDPEAIIREADIVIAACGQAHMIKGNWIKPGAAVIDVGTNAVSDPSKKSGYRLVGDVDFAEASK 265

  Fly   297 VAGHLTPVPGGVGPMTVAMLMKNTVRSAAR 326
            |||.:|||||||||||||||::|||..|.|
plant   266 VAGFITPVPGGVGPMTVAMLLRNTVDGAKR 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pug	NP_001014614.1	FolD	39..330	CDD:223268	158/289 (55%)
		THF_DHG_CYH	40..159	CDD:279147	51/118 (43%)
		NAD_bind_m-THF_DH_Cyclohyd	154..324	CDD:133448	106/170 (62%)
		FTHFS	350..968	CDD:279592
AT3G12290	NP_187837.1	PLN02516	1..299	CDD:178131	159/290 (55%)
		THF_DHG_CYH	11..127	CDD:279147	51/118 (43%)
		NAD_bind_m-THF_DH_Cyclohyd	122..294	CDD:133448	106/171 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	196	1.000	Domainoid score	I900
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100216
Panther	1	1.100	-	-	O	PTHR48099
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910