DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pug and AT2G38660

DIOPT Version :9

Sequence 1:	NP_001014614.1	Gene:	pug / 41279	FlyBaseID:	FBgn0020385	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_001118472.1	Gene:	AT2G38660 / 818448	AraportID:	AT2G38660	Length:	352	Species:	Arabidopsis thaliana

Alignment Length:	288	Identity:	139/288 - (48%)
Similarity:	189/288 - (65%)	Gaps:	4/288 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 IISGTAVAKSIREELRNEVTAMSKQLADFVPGLRIVQVGGREDSNVYIRMKIKAATEIGIDAAHV 104
            :|.|..:|:.||.::.:||..|.|.:.. ||||.:|.||.:.||..|:|.||||..|.||.:...
plant    65 VIDGNVIAEEIRTKIISEVGKMKKAVGK-VPGLAVVLVGEQRDSQTYVRNKIKACEETGIKSVLA 128

  Fly   105 QLPRSITEVELLDKINDLNEDPRVHGIIVQMPLDCDTPIDSHRITDAVSPEKDVDGLHTVNEGRL 169
            :||...||.:::..:...|||..:|||:||:||  ...::..:|.:.|..||||||.|.:|.|.|
plant   129 ELPEDCTEGQIISVLRKFNEDTSIHGILVQLPL--PQHLNESKILNMVRLEKDVDGFHPLNVGNL 191

  Fly   170 AI-GDLGGFLPCTPWGCLELIRRSGVEIAGARAVVLGRSKIVGTPAAELLKWANATVTVCHSKTR 233
            |: |....|:.|||.||:||:.|:||||||..|||:|||.|||.|.:.||:..:|||:..|:.|:
plant   192 AMRGREPLFVSCTPKGCVELLIRTGVEIAGKNAVVIGRSNIVGLPMSLLLQRHDATVSTVHAFTK 256

  Fly   234 NLEEITRSADILVVGIGVAEMVKGSWIKPGAVVIDCGINVKPDASKASGSKLVGDVDYAEALQVA 298
            :.|.|||.|||::...|:..:|:|||:||||||||.|.....|:|...|.:|||||.|.|||.||
plant   257 DPEHITRKADIVIAAAGIPNLVRGSWLKPGAVVIDVGTTPVEDSSCEFGYRLVGDVCYEEALGVA 321

  Fly   299 GHLTPVPGGVGPMTVAMLMKNTVRSAAR 326
            ..:|||||||||||:.||:.||:.:|.|
plant   322 SAITPVPGGVGPMTITMLLCNTLEAAKR 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pug	NP_001014614.1	FolD	39..330	CDD:223268	139/288 (48%)
		THF_DHG_CYH	40..159	CDD:279147	46/118 (39%)
		NAD_bind_m-THF_DH_Cyclohyd	154..324	CDD:133448	94/170 (55%)
		FTHFS	350..968	CDD:279592
AT2G38660	NP_001118472.1	PLN02897	8..352	CDD:178485	139/288 (48%)
		THF_DHG_CYH	65..181	CDD:279147	46/118 (39%)
		NAD_bind_m-THF_DH_Cyclohyd	177..348	CDD:133448	94/170 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	196	1.000	Domainoid score	I900
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48099
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010