DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14688 and PHYHD1

DIOPT Version :9

Sequence 1:	NP_001097740.1	Gene:	CG14688 / 41275	FlyBaseID:	FBgn0037819	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_777593.2	Gene:	PHYHD1 / 254295	HGNCID:	23396	Length:	297	Species:	Homo sapiens

Alignment Length:	174	Identity:	65/174 - (37%)
Similarity:	95/174 - (54%)	Gaps:	17/174 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LDELNENGYIVIEDFLTAEEVDSLYQ-AGRALC-LDAPQNNRKIFSTIKQED--AQGKELYFMES 66
            |.:..::|::|:|.||:|||..::.| .|..:. :|.|.:.|..|||.::|.  |||...||:.|
Human     9 LQKFQQDGFLVLEGFLSAEECVAMQQRIGEIVAEMDVPLHCRTEFSTQEEEQLRAQGSTDYFLSS 73

  Fly    67 GDKVRYFFEKGAVGDEGQLLVDPMIALNKVGHALHVEHPAFNAITFSNRVREICWQLNYNKPAVC 131
            |||:|:|||||...::|..||.|..::||:|||||...|.|.:||.|.:|:.:...|....|.|.
Human    74 GDKIRFFFEKGVFDEKGNFLVPPEKSINKIGHALHAHDPVFKSITHSFKVQTLARSLGLQMPVVV 138

  Fly   132 QSMYIYKNPGVGGEVTPHQDSWFLHTDPNSAVGFWLALEDCTLQ 175
            |||||:|:|             .:.|.|:.....|.....|..|
Human   139 QSMYIFKSP-------------LIRTPPSCTRSPWAGCWACGSQ 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14688	NP_001097740.1	PhyH	11..252	CDD:283399	64/169 (38%)
PHYHD1	NP_777593.2	2OG-FeII_Oxy	12..>147	CDD:304390	58/134 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144915
Domainoid	1	1.000	213	1.000	Domainoid score	I2771
eggNOG	1	0.900	-	-		E1_COG5285
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14939
Inparanoid	1	1.050	245	1.000	Inparanoid score	I3297
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55076
OrthoDB	1	1.010	-	-		D1316775at2759
OrthoFinder	1	1.000	-	-		FOG0005799
OrthoInspector	1	1.000	-	-		oto89257
orthoMCL	1	0.900	-	-		OOG6_103405
Panther	1	1.100	-	-	LDO	PTHR20883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5439
SonicParanoid	1	1.000	-	-		X4187
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800