Protein Alignment CG6465 and CPS1

DIOPT Version :9

• Sequence 1: NP_650004.1
• Gene: CG6465 / 41274
• FlyBaseID: FBgn0037818
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_012363.1
• Gene: CPS1 / 853267
• SGDID: S000003708
• Length: 576
• Species: Saccharomyces cerevisiae
• Alignment Length: 512
• Identity: 118/512 - (23%)
• Similarity: 185/512 - (36%)
• Gaps: 149/512 - (29%)

  Fly     9 DEEIQYFREYLRIPSVHPD--PDYAPCVEFLRRQANLMDLPMKVY---------YPANEQNPVVV 62
            :..|:.....:|||:|..|  |:.|...:|.:....|.|...|.:         ...||..  ::
Yeast    88 NSSIEKLSNAVRIPTVVQDKNPNPADDPDFYKHFYELHDYFEKTFPNIHKHLKLEKVNELG--LL 150

  Fly    63 LTWKGLNPELPSILLNSHMDVVPVFPE---NWTHPPFGADID-EEGRIFARGTQDMKSVGMQHLA 123
            .||:|.:|:|..:||.:|.|||||..|   :|..|||....| |...::.||:.|.|::.:....
Yeast   151 YTWEGSDPDLKPLLLMAHQDVVPVNNETLSSWKFPPFSGHYDPETDFVWGRGSNDCKNLLIAEFE 215

  Fly   124 AVRALKRSGAKFKRTIHISFVADEEMGG-------------RYGMRPFVPTED--FRALNVGFAM 173
            |:..|...|.|..|||.:|...|||..|             |||       :|  :..::.|
Yeast   216 AIEQLLIDGFKPNRTIVMSLGFDEEASGTLGAASLASFLHERYG-------DDGIYSIIDEG--- 270

  Fly   174 DEGLASPDEQL----PLFYAERAVWRVYFNISGTAGHGSL------------LLPNTAGEKLNY- 221
             ||:...|:.:    |: .||:.......:|.|..||.|:            |:........:|
Yeast   271 -EGIMEVDKDVFVATPI-NAEKGYVDFEVSILGHGGHSSVPPDHTTIGIASELITEFEANPFDYE 333

  Fly   222 ----------------------------IVGKMMEFRRSQ--VQRLQNNPELVIGDVTTINLTKL 256
                                        |:|.....||..  |:.:.|...|.....||..:..:
Yeast   334 FEFDNPIYGLLTCAAEHSKSLSKDVKKTILGAPFCPRRKDKLVEYISNQSHLRSLIRTTQAVDII 398

  Fly   257 GGGVQSNVVPPLLMVCFDCRLALDVDFEE-FEANLH---KWCADVG-----------------GG 300
            .|||::|.:|.......:.|:.|.....| ||.|:.   |.....|                 |.
Yeast   399 NGGVKANALPETTRFLINHRINLHSSVAEVFERNIEYAKKIAEKYGYGLSKNGDDYIIPETELGH 463

  Fly   301 IEITYEQKQPKVPPTAIDGSNPFW--LA------FKKA----TDEMHISIKPQIFTGGTDSRY-- 351
            |:||..::....|.:  ..|.|.|  ||      |:..    .:|.:::  ..:|:|.||::|
Yeast   464 IDITLLRELEPAPLS--PSSGPVWDILAGTIQDVFENGVLQNNEEFYVT--TGLFSGNTDTKYYW 524

  Fly   352 ------IRAVG----IPALGFSPMNNTPVLLHDHDEFIQADIYLRGVQIFQKIISNI 398
                  .|.||    |..|         ..||..:|.:....:|..:....:.|.|:
Yeast   525 NLSKNIYRFVGSIIDIDLL---------KTLHSVNEHVDVPGHLSAIAFVYEYIVNV 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	118/512 (23%)
		M20_AcylaseI_like	8..399	CDD:193524	118/512 (23%)
CPS1	NP_012363.1	M20_yscS	91..570	CDD:349923	116/505 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I2755
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.854522	Normalized mean entropy	S2324
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46677
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2059
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.790