DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6465 and DUG2

DIOPT Version :10

Sequence 1:NP_650004.1 Gene:CG6465 / 41274 FlyBaseID:FBgn0037818 Length:401 Species:Drosophila melanogaster
Sequence 2:NP_009840.3 Gene:DUG2 / 852584 SGDID:S000000485 Length:878 Species:Saccharomyces cerevisiae


Alignment Length:408 Identity:76/408 - (18%)
Similarity:127/408 - (31%) Gaps:114/408 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 TSKW--------ESDEEIQYFREYLRIPSVHPDPDYAPCVEFLRRQANLMDLPMKVYYPANEQ-- 57
            |:.|        .::|.:...||.:...:|....|....:...|....|..|.:| :...|.|  
Yeast   421 TNLWAAYQSASLNNEEMLNTLRELISFQTVSQSKDTTNTLSLRRCAIYLQQLFLK-FGATNSQLF 484

  Fly    58 ------NPVVVLTWKGLNPELPS--------ILLNSHMDVVP---VFPENWTHPPFGADIDEEGR 105
                  ||||...::| |.::..        ||...|.||:.   .|  ||...||.... |.|.
Yeast   485 PLPDGGNPVVFAYFQG-NGKVSQVKGAKKKRILWYGHYDVISSGNTF--NWNTDPFTLTC-ENGY 545

  Fly   106 IFARGTQDMKSVGMQHLAAVRALKRSGAKFKRTIHISFVADEEMGGRYGMRPFVPTEDFRALNVG 170
            :..||..|.|...:..:.:|..|.:.|......:.: ....||:|.....:......|....::.
Yeast   546 LKGRGVSDNKGPLVSAIHSVAYLFQQGELVNDVVFL-VEGSEEIGSASLKQVCEKYHDIIGKDID 609

  Fly   171 FAMDEGLASPDEQLP-LFYAERAVWRVYFNI--------SGTAG--------------------H 206
            :.:.......|::.| |.|..|.|......:        ||..|                    .
Yeast   610 WILLSNSTWVDQEHPCLNYGLRGVINAQIKVWSDKPDGHSGLNGGVYDEPMVNLVKIVSKLQNEQ 674

  Fly   207 GSLLLPNTAGEKLNYIVGKMMEFRRSQVQRLQNNPELV-IGDVTTI-----NLT---------KL 256
            ..:::||        ....:.:....:.||.|...||. |.:.||:     |.|         |.
Yeast   675 NEIMIPN--------FYSPLKDLTEEEYQRFQKITELANIDENTTVQDLITNWTKPSLSMTTVKF 731

  Fly   257 GGGVQSNVVPPLLMVCFDCRLALDVDFEEFEANLHKWCADVGGGIEITYEQKQPKVPPTAIDGSN 321
            .|.....|:|..:.:....||..:...|:.:.:|..:..:                         
Yeast   732 SGPGNITVIPKSVTMGISIRLVPEQSVEQVKRDLKAYLEE------------------------- 771

  Fly   322 PFWLAFKKATDEMHISIK 339
                :||:...:.|:.||
Yeast   772 ----SFKQLKSQNHLEIK 785

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6465NP_650004.1 Ac-peptdase-euk 1..401 CDD:273850 76/408 (19%)
DUG2NP_009840.3 WD40 19..336 CDD:475233
WD40 repeat 23..60 CDD:293791
WD40 repeat 74..121 CDD:293791
WD40 repeat 126..158 CDD:293791
WD40 repeat 166..213 CDD:293791
WD40 repeat 226..280 CDD:293791
WD40 repeat 288..324 CDD:293791
WD40 repeat 343..372 CDD:293791
M20_dipept_like_DUG2_type 437..878 CDD:349926 73/392 (19%)
Blue background indicates that the domain is not in the aligned region.

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