DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6465 and AT1G44820

DIOPT Version :9

Sequence 1:	NP_650004.1	Gene:	CG6465 / 41274	FlyBaseID:	FBgn0037818	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_175103.2	Gene:	AT1G44820 / 841046	AraportID:	AT1G44820	Length:	438	Species:	Arabidopsis thaliana

Alignment Length:	417	Identity:	156/417 - (37%)
Similarity:	241/417 - (57%)	Gaps:	23/417 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATSKWESDEEIQYFREYLRIPSVHPDPDYAPCVEFLRRQANLMDLPMK-VYYPANEQNPVVVLT 64
            :.:|..|.|..|..|::|||..:.||:|:|...:.||..||..:.|..| :.:.:.:  |::::|
plant    19 LQSSSSEEDTPITRFQQYLRFNTAHPNPNYTAPISFLINQAQSIGLTTKTIEFISGK--PILLIT 81

  Fly    65 WKGLNPELPSILLNSHMDVVPVFPENWTHPPFGADIDEEGRIFARGTQDMKSVGMQHLAAVRALK 129
            |.|.||.|||||.|||:|.||...|.||:|||.|....:|.|:|||.||.|.:|:|:|.::|.||
plant    82 WLGSNPNLPSILFNSHLDSVPAESEKWTYPPFSAHKTIDGHIYARGAQDDKCIGVQYLESIRNLK 146

  Fly   130 RSGAKFKRTIHISFVADEEMGGRYGMRPFVPTEDFRALNVGFAMDEGLASPDEQLPLFYAERAVW 194
            ..|....||||||:|.:||:||..||..|..:.:|:.||:|||||||.|:|.::..:|||:|..|
plant   147 SRGFSPLRTIHISYVPEEEIGGFDGMMKFAASSEFKDLNLGFAMDEGQANPGDEFRVFYADRVPW 211

  Fly   195 RVYFNISGTAGHGSLLLPNTAGEKLNYIVGKMMEFRRSQVQRLQNNPELVIGDVTTINLTKLGGG 259
            .......|..|||:.|..|:|.|.|...|..:..||.||...::.. :....:|.::|...|..|
plant   212 HFVIKAEGIPGHGAKLYDNSAMENLMKSVELISRFRESQFDFVKAG-KAAYSEVISVNPVYLKAG 275

  Fly   260 VQS------NVVPPLLMVCFDCRLALDVDFEEFEANL-HKWCADVGGGIEITYE-QKQPKVPP-- 314
            ..:      |:.|......:|.||....|.:..:..: .:|...:.   .:||. |::.|:..
plant   276 TPTTTGFVMNMQPSEAEAGYDLRLPPMADPDVMKKRIAEEWAPSIR---NMTYSIQEKGKLRDHL 337

  Fly   315 -----TAIDGSNPFWLAFKKATDEMHISI-KPQIFTGGTDSRYIRAVGIPALGFSPMNNTPVLLH 373
                 |.::.|||:|..||:|.:.|...: ||:|....||||:||.:|||..|||||.|||:|||
plant   338 GRPIMTPVNDSNPWWSIFKQAVEAMGGKLAKPEILASTTDSRFIRTLGIPTFGFSPMTNTPILLH 402

  Fly   374 DHDEFIQADIYLRGVQIFQKIISNIAN 400
            ||:||::..::::|:::::.:||.:::
plant   403 DHNEFLKDTVFMKGIEVYESVISALSS 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	156/417 (37%)
CG6465	NP_650004.1	M20_AcylaseI_like	8..399	CDD:193524	154/407 (38%)
AT1G44820	NP_175103.2	Ac-peptdase-euk	19..430	CDD:273850	156/417 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	275	1.000	Domainoid score	I418
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	323	1.000	Inparanoid score	I697
OMA	1	1.010	-	-		QHG55259
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	1	1.000	-	-		FOG0001520
OrthoInspector	1	1.000	-	-		mtm1187
orthoMCL	1	0.900	-	-		OOG6_100626
Panther	1	1.100	-	-	O	PTHR45892
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X958
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840