DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6465 and AQI

DIOPT Version :9

Sequence 1:	NP_650004.1	Gene:	CG6465 / 41274	FlyBaseID:	FBgn0037818	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_849516.1	Gene:	AQI / 829978	AraportID:	AT4G38220	Length:	433	Species:	Arabidopsis thaliana

Alignment Length:	403	Identity:	158/403 - (39%)
Similarity:	225/403 - (55%)	Gaps:	13/403 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DEEIQYFREYLRIPSVHPDPDYAPCVEFLRRQANLMDLPMKVYYPANEQNPVVVLTWKGLNPELP 73
            |..:..|:|||||.:|.|:|:|...|:|:..||..:.|..:. ....:..|:::|.|.|.:|.||
plant    22 DAIVSRFQEYLRINTVQPNPEYYKAVDFIISQAKPLSLESQT-IEFVKGKPLLLLKWVGSDPTLP 85

  Fly    74 SILLNSHMDVVPVFPENWTHPPFGADIDEEGRIFARGTQDMKSVGMQHLAAVRALKRSGAKFKRT 138
            :.|||||.||||.....|||.|..|.:|..|.|:|||:||||.||||:|.|:|.|:.||.|..|:
plant    86 AFLLNSHTDVVPFEDSKWTHHPLQAHMDHHGDIYARGSQDMKCVGMQYLEAIRKLQASGFKPLRS 150

  Fly   139 IHISFVADEEMGGRYGMRPFVPTEDFRALNVGFAMDEGLASPDEQLPLFYAERAVWRVYFNISGT 203
            :::|||.|||:||..|...|..::.|::||:...:||||.||.|...:||.||:.|.:.....|.
plant   151 VYLSFVPDEEIGGHDGAEKFAESQLFKSLNIAIVLDEGLPSPTESYRVFYGERSPWWLVIKAKGP 215

  Fly   204 AGHGSLLLPNTAGEKLNYIVGKMMEFRRSQVQRLQNNPELVIGDVTTINLTKLGGGVQS------ 262
            .|||:.|..|:|.|.|...:..:..||.||...|:.. .:..|||.::|:..|..|..|
plant   216 PGHGAKLYDNSAMENLLKSIESIRRFRASQFDLLKAG-GIAEGDVVSVNMAFLKAGTPSPTGFVM 279

  Fly   263 NVVPPLLMVCFDCRLALDVDFEEFEANLHKWCADVGGGIEITYEQKQPKVPP----TAIDGSNPF 323
            |:.|......||.|:...||.|..|..|.:..|.....:.....|.:.|:..    ||.|.|||:
plant   280 NLQPSEAEAGFDIRVPPSVDAEALERRLVEEWAPAARNMSFELGQFKQKLTGKQFLTAADDSNPW 344

  Fly   324 WLAFKKATDEM-HISIKPQIFTGGTDSRYIRAVGIPALGFSPMNNTPVLLHDHDEFIQADIYLRG 387
            |...:.|..|. ..:.||:||...||:||.|..|:||.||||::|||.|||||:|::....||:|
plant   345 WGLLENAVKEAGGRTSKPEIFPASTDARYFRKAGVPAFGFSPISNTPSLLHDHNEYLGKAEYLKG 409

  Fly   388 VQIFQKIISNIAN 400
            ::::..||...|:
plant   410 IEVYVSIIKAYAS 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	158/403 (39%)
CG6465	NP_650004.1	M20_AcylaseI_like	8..399	CDD:193524	157/400 (39%)
AQI	NP_849516.1	Ac-peptdase-euk	21..422	CDD:273850	157/401 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	275	1.000	Domainoid score	I418
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110440
Inparanoid	1	1.050	323	1.000	Inparanoid score	I697
OMA	1	1.010	-	-		QHG55259
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	1	1.000	-	-		FOG0001520
OrthoInspector	1	1.000	-	-		mtm1187
orthoMCL	1	0.900	-	-		OOG6_100626
Panther	1	1.100	-	-	LDO	PTHR45892
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X958
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840