Protein Alignment CG6465 and CNDP2

DIOPT Version :10

• Sequence 1: NP_650004.1
• Gene: CG6465 / 41274
• FlyBaseID: FBgn0037818
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_060705.2
• Gene: CNDP2 / 55748
• HGNCID: 24437
• Length: 475
• Species: Homo sapiens
• Alignment Length: 491
• Identity: 92/491 - (18%)
• Similarity: 172/491 - (35%)
• Gaps: 131/491 - (26%)

  Fly     9 DEEIQYFREYLRIPSVHPDPD-----------YAPCVEFLRRQANLMDLPMKVYYPANEQNPV-- 60
            |..|:...:::.|.||...|:           .|..|:.|.....|:|:. |...|...:.|:
Human    16 DRYIKKLAKWVAIQSVSAWPEKRGEIRRMMEVAAADVKQLGGSVELVDIG-KQKLPDGSEIPLPP 79

  Fly    61 VVLTWKGLNPELPSILLNSHMDVVP-VFPENWTHPPFGADIDEEGRIFARGTQDMKSVGMQHLAA 124
            ::|...|.:|:..::.:..|:||.| ...:.|...||.. ::.:|:::.||:.|.|......:.|
Human    80 ILLGRLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTL-VERDGKLYGRGSTDDKGPVAGWINA 143

  Fly   125 VRALKRSGAKFKRTIHISFVADEEMGGRYGM--------RPFVPTEDFRALNVGFAMDEGLASPD 181
            :.|.:::|.:....:.......||.|.. |:        ..|....|:..::..:.:  |...|
Human   144 LEAYQKTGQEIPVNVRFCLEGMEESGSE-GLDELIFARKDTFFKDVDYVCISDNYWL--GKKKP- 204

  Fly   182 EQLPLFYAERAVWRVYFNI----------SGTAG--------------------HGSLLLPNTAG 216
               .:.|..|.:  .||.|          ||..|                    .|::|:|.
Human   205 ---CITYGLRGI--CYFFIEVECSNKDLHSGVYGGSVHEAMTDLILLMGSLVDKRGNILIPG--- 261

  Fly   217 EKLNYIVGKMMEFRRSQVQRLQNNPELVIGDV--------------------TTINLTKLGGGVQ 261
              :|..|..:.|........:..:.|....||                    .:::|..:.|...
Human   262 --INEAVAAVTEEEHKLYDDIDFDIEEFAKDVGAQILLHSHKKDILMHRWRYPSLSLHGIEGAFS 324

  Fly   262 SN----VVPPLLMVCFDCRL----ALDVDFEEFEANLHKWCADVGGGIEITYEQKQPKV------ 312
            .:    |:|..::..|..||    ..:|..|:..:.|.|..|::....|.       ||
Human   325 GSGAKTVIPRKVVGKFSIRLVPNMTPEVVGEQVTSYLTKKFAELRSPNEF-------KVYMGHGG 382

  Fly   313 PPTAIDGSNPFWLAFKKATDEMHISIKPQIF-TGGTDSRYIRAVGIP-ALGFSPMNNTPVLL--- 372
            .|...|.|:|.:||.::|...: ..::|.:. .||:         || .|.|.......|:|
Human   383 KPWVSDFSHPHYLAGRRAMKTV-FGVEPDLTREGGS---------IPVTLTFQEATGKNVMLLPV 437

  Fly   373 -------HDHDEFIQADIYLRGVQIFQKIISNIANV 401
                   |..:|.:....|:.|.::....:..::.:
Human   438 GSADDGAHSQNEKLNRYNYIEGTKMLAAYLYEVSQL 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	92/489 (19%)
CNDP2	NP_060705.2	M20_dipept_like_CNDP	7..473	CDD:349925	92/489 (19%)