DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6465 and Pm20d1

DIOPT Version :9

Sequence 1:	NP_650004.1	Gene:	CG6465 / 41274	FlyBaseID:	FBgn0037818	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_001102538.1	Gene:	Pm20d1 / 498226	RGDID:	1564063	Length:	503	Species:	Rattus norvegicus

Alignment Length:	461	Identity:	109/461 - (23%)
Similarity:	179/461 - (38%)	Gaps:	86/461 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SDEEIQYFREYL----RIPSV---HPDPDYAPCVEF---LRR------QANLMDLPMKVYYPANE 56
            |:||....:|.|    |||:|   |.:.:.....||   :|:      .:||:
  Rat    44 SEEERVAMKEALKGAIRIPTVSFSHEESNTTALAEFGEYIRKAFPTVFHSNLI------------ 96

  Fly    57 QNPVV-----VLTWKGLNPELPSILLNSHMDVVPVFPENWTHPPFGADIDEEGRIFARGTQDMKS 116
            |:.||     :||.:|.:|.|...:|.:|.||||...|.|..||| :.:::.|.|..||..|.|:
  Rat    97 QHEVVGKYSHLLTVRGSDPSLQPYMLMAHFDVVPASEEGWEVPPF-SGLEQNGFIHGRGALDNKN 160

  Fly   117 VGMQHLAAVRALKRSGAKFKRTIHISFVADEEMGGRYGMRPFVPTEDFRALNVGFAMDEGLASPD 181
            ..|..|.|:..|.......||...|:...|||:.|..|.:........|.:.:.|.:|||....:
  Rat   161 SVMAVLQALELLLIRKYSPKRPFFIALGHDEEVSGTKGAQQISALLQTRGVQLAFLVDEGSFILE 225

  Fly   182 EQLP--------LFYAERAVWRVYFNISGTAGHGS---------LL-----------LPNTAGE- 217
            :.:|        :...|:....:...::.|.||.|         :|           :||..|.
  Rat   226 DFIPNLKKPFAMISVTEKGALDLMLQVNMTPGHSSAPPKETSIGILSAAVSRLEQTPMPNMFGNG 290

  Fly   218 ------KL---------NYIVGKMMEFRRSQVQRLQNNPELVIGDVTTINLTKLGGGVQSNVVPP 267
                  ||         |.|:|.:..||....:.::.||.......||..||....|::.||:||
  Rat   291 PLKKTLKLLANEFSFPTNIILGNLWLFRPIVSRVMERNPITNALVRTTTALTMFNAGIKVNVIPP 355

  Fly   268 LLMVCFDCRLALDVDFEEFEANLHKWCADVGGGIEITYEQKQPKVPPTAIDGSNPFWLAFKKATD 332
            |.....:.|:.......|....:....||  ..:::...:....:|.:..|.....:...::...
  Rat   356 LAQATVNFRIHPSQTVHEVVELVQNIVAD--DRVQLHVLRSFEPLPVSPSDDQAMGYQLLQQTIQ 418

  Fly   333 EMHISIK---PQIFTGGTDSRYIRAVGIPALGFSPMNNTP---VLLHDHDEFIQADIYLRGVQIF 391
            .:...:|   |.|..|.||:|:...:......|:|:...|   ..:|..:|.|..:.|...|:..
  Rat   419 SVFPEVKIIVPGICIGNTDTRHYVNLTNGLYRFNPVFLKPQDFSSVHGINEKISVESYQNQVKFI 483

  Fly   392 QKIISN 397
            .::|.|
  Rat   484 FELIQN 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	109/461 (24%)
CG6465	NP_650004.1	M20_AcylaseI_like	8..399	CDD:193524	109/461 (24%)
Pm20d1	NP_001102538.1	PRK08262	4..491	CDD:236208	109/461 (24%)
Pm20d1	NP_001102538.1	M20_yscS	53..488	CDD:193549	104/449 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820