DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6465 and darmin

DIOPT Version :9

Sequence 1:	NP_650004.1	Gene:	CG6465 / 41274	FlyBaseID:	FBgn0037818	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	XP_002941927.3	Gene:	darmin / 394903	XenbaseID:	XB-GENE-481839	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	476	Identity:	92/476 - (19%)
Similarity:	170/476 - (35%)	Gaps:	106/476 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DEEIQYFREYLRIPSVHPDPDYAPCVEFLRRQANL-MDLPMKV-----YYPANEQN--------- 58
            ||.||..::::.|.|...||...   :.|.:...| .|..:|:     .....||.
Frog    33 DEFIQRLKDWVAIESDSSDPSKR---DLLNKMMELTKDFILKLGGNVEMAEIGEQELSSGERIPL 94

  Fly    59 PVVVLTWKGLNPELPSILLNSHMDVVPV-FPENWTHPPFGADIDEEGRIFARGTQDMKSVGMQHL 122
            |.|:|...|.:...|::....||||.|. ..:.|...|:.. ::::|.::.|||.|.|...:..|
Frog    95 PPVILAELGNDKSKPTVCFYGHMDVQPAKQTDGWLTDPYTV-VEKDGNLYGRGTSDDKGQVLALL 158

  Fly   123 AAVRALKRSGAKFKRTIHISFVAD--EEMGGRYGMRPFV-PTEDFRALNVGFAMDEGLASPDEQL 184
            .|:.::...|.    .:::..|.:  ||:|.. |:...| ..:|....||.:.:........::.
Frog   159 HALESVNVMGL----PVNVKLVIEGMEEVGSD-GLEKLVEDKKDTFFSNVDYIVVTDTPWLSKKP 218

  Fly   185 PLFYAERAVWRVYFNISGTA----------------------------GHGSLLLPN-------- 213
            .:.|..|.....:..:.|:.                            |.|.:|:|.
Frog   219 GITYGARGNCYFFLEVQGSRRDLHSGGFGGTVHEAMSDLIYLLNTLADGKGRILVPGIYEAVAPV 283

  Fly   214 TAGEKLNYIVGKMMEFRRSQVQR-------LQNNPE-LVIGDVTTINLTKLG------GGVQSNV 264
            :..|...|   |.:||.:.::|.       |.:..| |::......:||..|      |.....|
Frog   284 SENETDLY---KNLEFSQQEMQADTGVTQFLHDTKEDLLMHRWRYPSLTIHGIEGAFCGTGTKTV 345

  Fly   265 VPPLLMVCFDCRLALDVDFEEFEANLHKWCADVGGGIEITY-EQKQPK---------VPPTAIDG 319
            :|..::..|..|...::|....|..:..:       :|..: |:|.|.         ..|...|.
Frog   346 IPAKVIGKFSMRQVPNMDPSVVEKQVTDY-------LEAKFSERKSPNKIKVKMVIGAKPWLADM 403

  Fly   320 SNPFWLAFKKATDEMHISIKPQIFTGGT-----DSRYIRAVGIPALGFSPMNNTPVLLHDHDEFI 379
            :.|.:||.::|...:.......|..|||     ....:....:..||....::.|   |..:|.|
Frog   404 NEPQYLAARRAVKRVFNLEADMIRAGGTIPIAKTLEDVLGKSVMLLGIGGPDDAP---HGQNEKI 465

  Fly   380 QADIYLRGVQIFQKIISNIAN 400
            ....|:.|.:::...:..:::
Frog   466 SKYNYIEGTKLYASYLQELSS 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	92/476 (19%)
CG6465	NP_650004.1	M20_AcylaseI_like	8..399	CDD:193524	92/473 (19%)
darmin	XP_002941927.3	M20_dipept_like_CNDP	24..487	CDD:349925	92/476 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910