DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6465 and acy1

DIOPT Version :9

Sequence 1:	NP_650004.1	Gene:	CG6465 / 41274	FlyBaseID:	FBgn0037818	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	XP_009294786.1	Gene:	acy1 / 393970	ZFINID:	ZDB-GENE-040426-755	Length:	427	Species:	Danio rerio

Alignment Length:	396	Identity:	181/396 - (45%)
Similarity:	257/396 - (64%)	Gaps:	7/396 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DEEIQYFREYLRIPSVHPDPDYAPCVEFLRRQANLMDLPMKVYYPANEQNP---VVVLTWKGLNP 70
            |..:..||||||:.:|||:|||...::||.|.|..:.||||..    |..|   |.:::|.|..|
Zfish    29 DPSVTLFREYLRLKTVHPEPDYDAALKFLERMAEELALPMKKV----EVCPGRVVAIISWIGSRP 89

  Fly    71 ELPSILLNSHMDVVPVFPENWTHPPFGADIDEEGRIFARGTQDMKSVGMQHLAAVRALKRSGAKF 135
            ||.|::||||.|||||:.|:|.|.||.|..|.:|.|:|||.||||||.:|::.|:|.||.:|.:|
Zfish    90 ELKSVVLNSHTDVVPVYEEHWKHHPFAAVKDADGNIYARGAQDMKSVTIQYIEAIRRLKAAGKRF 154

  Fly   136 KRTIHISFVADEEMGGRYGMRPFVPTEDFRALNVGFAMDEGLASPDEQLPLFYAERAVWRVYFNI 200
            .||||::||.|||:||..||..||...:|:.||:|||:|||||:|.....:||.||..|.:....
Zfish   155 SRTIHLTFVPDEEVGGHKGMETFVKHPEFQKLNMGFALDEGLANPTNAYTVFYGERNPWWITVRC 219

  Fly   201 SGTAGHGSLLLPNTAGEKLNYIVGKMMEFRRSQVQRLQNNPELVIGDVTTINLTKLGGGVQSNVV 265
            .|:.||||..:.|||.|||..::...:|||..:.|||..:....:|||||||:|.:.|||..|||
Zfish   220 PGSPGHGSRFVENTAAEKLRRVINSFLEFREKEKQRLNTSECFTLGDVTTINMTMVKGGVAYNVV 284

  Fly   266 PPLLMVCFDCRLALDVDFEEFEANLHKWCADVGGGIEITYEQKQPKVPPTAIDGSNPFWLAFKKA 330
            |..:.|.||.|:...|:.:|||..:..||.:.|..:...:.||......|:.|.::|:|.||...
Zfish   285 PAEMDVSFDLRIPPTVNLQEFEEKIKVWCREAGEDVTYDFAQKHMDQNLTSTDENDPWWQAFSST 349

  Fly   331 TDEMHISIKPQIFTGGTDSRYIRAVGIPALGFSPMNNTPVLLHDHDEFIQADIYLRGVQIFQKII 395
            ...|::::|.:||...||||:||.||:||:||||||.||:|||||:|::...::|:|:|:::::|
Zfish   350 CKAMNMTLKKEIFPAATDSRFIREVGLPAIGFSPMNLTPILLHDHNEYLNEQVFLQGIQVYERLI 414

  Fly   396 SNIANV 401
            ..:|.|
Zfish   415 PALAGV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	180/394 (46%)
CG6465	NP_650004.1	M20_AcylaseI_like	8..399	CDD:193524	179/392 (46%)
acy1	XP_009294786.1	Ac-peptdase-euk	28..420	CDD:273850	180/394 (46%)
acy1	XP_009294786.1	M20_AcylaseI_like	28..418	CDD:193524	179/392 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582010
Domainoid	1	1.000	336	1.000	Domainoid score	I1081
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110440
Inparanoid	1	1.050	398	1.000	Inparanoid score	I1895
OMA	1	1.010	-	-		QHG55259
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	1	1.000	-	-		FOG0001520
OrthoInspector	1	1.000	-	-		otm26566
orthoMCL	1	0.900	-	-		OOG6_100626
Panther	1	1.100	-	-	LDO	PTHR45892
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2059
SonicParanoid	1	1.000	-	-		X958
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800