DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6465 and Cndp1

DIOPT Version :9

Sequence 1:	NP_650004.1	Gene:	CG6465 / 41274	FlyBaseID:	FBgn0037818	Length:	401	Species:	Drosophila melanogaster
Sequence 2:	NP_001007688.1	Gene:	Cndp1 / 307212	RGDID:	1359493	Length:	492	Species:	Rattus norvegicus

Alignment Length:	480	Identity:	97/480 - (20%)
Similarity:	177/480 - (36%)	Gaps:	127/480 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DEEIQYFREYLRI--PSVHPDPDYAPCVEFLRRQA----NLMDLPMKV--------YYPANEQ-- 57
            ||.:|..:|::.|  .||.|.|....  |..|..|    .|.:|..:|        ..|..:.
  Rat    22 DEFVQTLKEWVAIESDSVQPMPRLRQ--ELFRMMALAADKLRNLGARVDSVDLGSQQMPDGQSLP 84

  Fly    58 NPVVVLTWKGLNPELPSILLNSHMDVVPVFPEN-WTHPPFG-ADIDEEGRIFARGTQDMKSVGMQ 120
            .|.::|...|.:|:.||:....|:||.|...|: |...|:. .::|  |:::.||..|.|...:.
  Rat    85 TPPIILAELGNDPKKPSVCFYGHLDVQPAQKEDGWLTDPYTLTEVD--GKLYGRGATDNKGPVLA 147

  Fly   121 HLAAV---RALKRSGAKFKRTIHISFVAD-EEMGGRYGMRPFVPTED---FRALNVGFAMDEGLA 178
            .:.||   |||::.     ..:::.|:.: .|..|...:...|..|.   |..::. ..:.:.|.
  Rat   148 WINAVSTFRALQQD-----LPVNVKFILEGMEEAGSVALEELVKREKDNFFSGVDY-IVISDNLW 206

  Fly   179 SPDEQLPLFYAERAVWRVYFNI----------SGTAG--------------------HGSLLLPN 213
            ...::..|....|.  ..||.:          |||.|                    .|.:|:|.
  Rat   207 LSQKKPALTCGTRG--NCYFTVEVKCRDQDFHSGTFGGILNEPMADLVALLGSLVDSSGHILVPG 269

  Fly   214 --------TAGEKLNY--IVGKMMEFRR-SQVQR--LQNNPELV--IGDVTTINLTKLGGGVQ-- 261
                    |..||..|  |...:.|::: |:|:|  .....||:  :....::::..:.|...
  Rat   270 IYDQMAPITEEEKTMYENIDLDLEEYQKSSRVERFLFDTKEELLTHLWRYPSLSIHGIEGAFDEP 334

  Fly   262 --SNVVPPLLMVCFDCRLA--LDVDFEEFEANLHKWCADVGGGIEITYEQKQP--KVPPTAIDGS 320
              ..|:|..::..|..||.  :.....|.:...|         :|..:.::..  |:..:.:.|.
  Rat   335 GTKTVIPGRVLGKFSIRLVPHMTPSVVETQVTQH---------LEAVFSKRNSFNKMAVSMVLGL 390

  Fly   321 NPF--------WLAFKKATDEMHISIKPQIFTGGTDSRYIRAVGIP-ALGFSPMNNTPVLL---- 372
            .|:        :||.::|...: ..:.|.:...|:.        || |..|..:....|::
  Rat   391 QPWTANINGTQYLAARRAIQTV-FGVDPDMIQDGST--------IPIAKIFQDITQKSVMMLPLG 446

  Fly   373 ------HDHDEFIQADIYLRGVQIF 391
                  |..:|.|....|::|.::|
  Rat   447 AVDDGEHSQNEKINRWNYIQGSKLF 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	97/480 (20%)
CG6465	NP_650004.1	M20_AcylaseI_like	8..399	CDD:193524	97/480 (20%)
Cndp1	NP_001007688.1	M20_dipept_like_CNDP	13..481	CDD:193551	97/480 (20%)
Cndp1	NP_001007688.1	PRK08201	16..481	CDD:169276	97/480 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810