Protein Alignment CG6465 and PM20D1

DIOPT Version :9

• Sequence 1: NP_650004.1
• Gene: CG6465 / 41274
• FlyBaseID: FBgn0037818
• Length: 401
• Species: Drosophila melanogaster
• Sequence 2: NP_689704.4
• Gene: PM20D1 / 148811
• HGNCID: 26518
• Length: 502
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 96/416 - (23%)
• Similarity: 149/416 - (35%)
• Gaps: 99/416 - (23%)

  Fly    57 QNPVV-----VLTWKGLNPELPSILLNSHMDVVPVFPENWTHPPFGADIDEEGRIFARGTQDMKS 116
            |:.||     :.|.:|.:|.|...||.:|.||||...|.|..||| :.::.:|.|:.|||.|.|:
Human    97 QHEVVEEYSHLFTIQGSDPSLQPYLLMAHFDVVPAPEEGWEVPPF-SGLERDGIIYGRGTLDDKN 160

  Fly   117 VGMQHLAAVRALKRSGAKFKRTIHISFVADEEMGGRYGMRPFVPTEDFRALNVGFAMDEGLASPD 181
            ..|..|.|:..|.......:|:..||...|||..|. |.:........|.:.:.|.:|||....|
Human   161 SVMALLQALELLLIRKYIPRRSFFISLGHDEESSGT-GAQRISALLQSRGVQLAFIVDEGGFILD 224

  Fly   182 EQLPLF--------YAERAVWRVYFNISGTAGHGS------------------------------ 208
            :.:|.|        .:|:....:...::.|:||.|
Human   225 DFIPNFKKPIALIAVSEKGSMNLMLQVNMTSGHSSAPPKETSIGILAAAVSRLEQTPMPIIFGSG 289

  Fly   209 ---LLLPNTAGE---KLNYIVGKMMEFRRSQVQRLQNNP--ELVIGDVTTINLTKLGGGVQSNVV 265
               .:|...|.|   .:|.|:.....|.....:.::.||  ..:|.  ||..||....||:.||:
Human   290 TVVTVLQQLANEFPFPVNIILSNPWLFEPLISRFMERNPLTNAIIR--TTTALTIFKAGVKFNVI 352

  Fly   266 PPLLMVCFDCRLALDVDFEEF-----------EANLHKWCA----------DVGGGIEITYEQKQ 309
            ||:.....:.|:......:|.           ....|...|          |...|.::..:..|
Human   353 PPVAQATVNFRIHPGQTVQEVLELTKNIVADNRVQFHVLSAFDPLPVSPSDDKALGYQLLRQTVQ 417

  Fly   310 PKVPPTAIDGSNPFWLAFKKATDEMHISIKPQIFTGGTDSRYIRAVGIPALGFSPMNNTP---VL 371
            ...|                   |::|: .|....|.||||:...:......|.|:...|   ..
Human   418 SVFP-------------------EVNIT-APVTSIGNTDSRFFTNLTTGIYRFYPIYIQPEDFKR 462

  Fly   372 LHDHDEFIQADIYLRGVQIFQKIISN 397
            :|..:|.|....|...|:...::|.|
Human   463 IHGVNEKISVQAYETQVKFIFELIQN 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6465	NP_650004.1	Ac-peptdase-euk	1..401	CDD:273850	96/416 (23%)
		M20_AcylaseI_like	8..399	CDD:193524	96/416 (23%)
PM20D1	NP_689704.4	PRK08262	35..490	CDD:236208	96/416 (23%)
		M20_yscS	53..487	CDD:193549	94/413 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1432382at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2059
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850